Uveitis: Difference between revisions
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==Background== |
==Background== |
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+ | |||
β | * |
+ | *Inflammation of the uvea, which comprises the iris, ciliary body, and choroid, or of the retina |
β | ** |
+ | **Anterior: iritis, iridocyclitis |
β | ** |
+ | **Intermediate: pars planitis |
β | ** |
+ | **Posterior: choroiditis, retinitis, chorioretinitis |
β | ** |
+ | **Panuveitis |
==Differential Diagnosis== |
==Differential Diagnosis== |
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===Infectious causes=== |
===Infectious causes=== |
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+ | |||
⚫ | |||
β | * |
+ | *Anterior uveitis (10% infectious) |
+ | **[[Herpes simplex virus]] (by far the most common infectious cause) |
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⚫ | |||
β | ** |
+ | **[[Varicella-zoster virus]] |
β | ** |
+ | **[[Syphilis]] |
β | ** |
+ | **[[Tuberculosis]] |
β | ** |
+ | **[[Lyme disease]] |
+ | **[[Leprosy]] |
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β | * |
+ | *Intermediate uveitis (rarely infectious) |
β | ** |
+ | **[[Lyme disease]] |
β | * Posterior uveitis (50% infectious) |
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⚫ | |||
β | ** |
+ | **[[Toxoplasmosis]] |
β | ** |
+ | **[[Acute retinal necrosis]] from [[HSV]], [[VZV]], and [[CMV]] |
β | ** |
+ | **[[CMV]] retinitis, in immunocompromised patients |
β | ** [[Toxocara]] |
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β | ** |
+ | **[[Toxocara]] |
β | ** |
+ | **[[Syphilis]] |
+ | **[[Cat-scratch disease]] |
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β | ** |
+ | **[[Candida]] endophthalmitis |
β | ** |
+ | **[[West Nile virus]], causing a multifocal chorioretinitis |
β | * |
+ | *Panuveitis |
β | ** [[Syphilis]] |
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β | ** |
+ | **[[Syphilis]] |
+ | **[[Tuberculosis]] |
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β | ** |
+ | **[[Candida]] endophthalmitis |
β | ** |
+ | **[[Leptospirosis]], without retinal or choroidal lesions |
β | * |
+ | *Other |
β | ** |
+ | **[[Brucella]], causing a chronic relapsing uveitis that is typically posterior but can be anterior or panuveitis[[CiteRef::rolando2008oc]] |
β | ** [[Chikungunya]] |
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β | ** |
+ | **[[Chikungunya]] |
β | ** |
+ | **[[Ebola virus]] |
⚫ | |||
+ | |||
+ | == Clinical Manifestations == |
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+ | |||
+ | * Anterior: painful red eye and vision loss |
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+ | * Intermediate: vision loss with floaters, usually painless (and rarely infectious) |
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+ | * Posterior: painless vision loss |
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[[Category:Ophthalmology]] |
[[Category:Ophthalmology]] |
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+ | [[Category:Infectious diseases]] |
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+ | [[Category:Eye infections]] |
Latest revision as of 10:38, 12 August 2020
Background
- Inflammation of the uvea, which comprises the iris, ciliary body, and choroid, or of the retina
- Anterior: iritis, iridocyclitis
- Intermediate: pars planitis
- Posterior: choroiditis, retinitis, chorioretinitis
- Panuveitis
Differential Diagnosis
Infectious causes
- Anterior uveitis (10% infectious)
- Herpes simplex virus (by far the most common infectious cause)
- Varicella-zoster virus
- Syphilis
- Tuberculosis
- Lyme disease
- Leprosy
- Intermediate uveitis (rarely infectious)
- Posterior uveitis (50% infectious)
- Toxoplasmosis
- Acute retinal necrosis from HSV, VZV, and CMV
- CMV retinitis, in immunocompromised patients
- Toxocara
- Syphilis
- Cat-scratch disease
- Candida endophthalmitis
- West Nile virus, causing a multifocal chorioretinitis
- Panuveitis
- Syphilis
- Tuberculosis
- Candida endophthalmitis
- Leptospirosis, without retinal or choroidal lesions
- Other
- Brucella, causing a chronic relapsing uveitis that is typically posterior but can be anterior or panuveitis1
- Chikungunya
- Ebola virus
- Zika virus
Clinical Manifestations
- Anterior: painful red eye and vision loss
- Intermediate: vision loss with floaters, usually painless (and rarely infectious)
- Posterior: painless vision loss
References
- ^ Isaias Rolando, Liset Olarte, Gustavo Vilchez, Marina Lluncor, Larissa Otero, Mark Paris, Carlos Carrillo, Eduardo Gotuzzo. Ocular Manifestations Associated with Brucellosis: A 26βYear Experience in Peru. Clinical Infectious Diseases. 2008;46(9):1338-1345. doi:10.1086/529442.