Schistosoma: Difference between revisions

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Schistosoma
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m (Text replacement - "== Clinical Presentation" to "== Clinical Manifestations")
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* Fresh water exposure in endemic countries
 
* Fresh water exposure in endemic countries
   
== Clinical Presentation ==
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== Clinical Manifestations ==
   
 
== Investigations ==
 
== Investigations ==

Revision as of 08:02, 2 August 2020

  • Infection with a species of the genus Schistosoma

Species

Risk Factors

  • Fresh water exposure in endemic countries

Clinical Manifestations

Investigations

  • Labs
    • CBC, showing eosinophilia
    • Schisto serology (only positive 6 weeks after infection)
    • Egg detection in stool, urine, semen, or tissue biopsy
  • Imaging
    • Eggs can cause granulomatous disease in various organs
    • Bladder polyps and obstruction may be seen on ultrasound

Management

  • Acute
  • Chronic
    • Praziquantel 20-40 mg/kg or 40-60 mg/kg (if at risk for S. japonica)
    • Given over one day split into 3 doses, then repeated 6 weeks later

Prognosis

  • Increased risk of squamous cell carcinoma, which increase with young age at infection, duration of infection, high burden of infection, and bladder wall fibrosis

References

  1. ^  Archana Asundi, Alina Beliavsky, Xing Jian Liu, Arash Akaberi, Guido Schwarzer, Zeno Bisoffi, Ana Requena-Méndez, Ian Shrier, Christina Greenaway. Prevalence of strongyloidiasis and schistosomiasis among migrants: a systematic review and meta-analysis. The Lancet Global Health. 2019;7(2):e236-e248. doi:10.1016/s2214-109x(18)30490-x.