Smudge cells: Difference between revisions

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Created page with "==Background== * Also called basket cells or Gumprecht shadows * Remnants of fragile leukocytes that are smeared during preparation of a blood film * Classically associated with CLL, where they represent ruptured diseased B cells * May also be seen in some infections or inflammatory conditions Category:Hematology"
 
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* Also called basket cells or Gumprecht shadows
* Also called basket cells or Gumprecht shadows
* Remnants of fragile leukocytes that are smeared during preparation of a blood film
* Remnants of fragile leukocytes that are smeared during preparation of a blood film

== Differential Diagnosis ==
* Classically associated with [[CLL]], where they represent ruptured diseased B cells
* Classically associated with [[CLL]], where they represent ruptured diseased B cells
* May also be seen in some infections or inflammatory conditions
* May also be seen in some infections (including [[infectious mononucleosis]]), post-cardiac arrest, inflammatory conditions
** Also solid-organ malignancies and artifact


[[Category:Hematology]]
[[Category:Hematology]]

Latest revision as of 20:04, 14 February 2025

Background

  • Also called basket cells or Gumprecht shadows
  • Remnants of fragile leukocytes that are smeared during preparation of a blood film

Differential Diagnosis

  • Classically associated with CLL, where they represent ruptured diseased B cells
  • May also be seen in some infections (including infectious mononucleosis), post-cardiac arrest, inflammatory conditions
    • Also solid-organ malignancies and artifact