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* Septic shock is sepsis with shock despite adequate resuscitation

* Severe septic shock caused by certain bacterial infections, primarily ''[[Staphylococcus aureus *Similar syndrome can be caused by toxin production of [[Clostridial toxic shock syndrome|''Clostridium sordelli'']]

...nitis]], [[sepsis]], [[myometritis]], and [[septic pulmonary emboli]] or [[septic pelvic thrombophlebitis]]

...ms include dysuria, suprapubic pain, flank pain, CVA tenderness, or septic shock ...es should not be included in any standardized order sets except for septic shock

|Severe sepsis or septic shock

...hock syndrome toxin 1 (TSST-1) is implicated in [[TSS|Staphylococcal toxic shock syndrome]] **Exotoxins B and C cause [[TSS|Staphylococcal toxic shock syndrome]] and also food poisoning

*Septic shock is sepsis with profound underlying circulatory and metabolic derangements ****May be beneficial in shock

*Severe complications include respiratory failure, septic shock, rhabdomyolysis, hemorrhage, and opportunistic infections

...scesses, latent infection, chronic pneumonia (similar to TB), or fulminant shock[[CiteRef::diemert2010th]][[CiteRef::meumann2011cl]] **Septic arthritis/OM (3-5%)

** Septic shock with need for vasopressors

** [[MRSA]] or SSTI or severe [[mucositis]] or septic shock: vancomycin 15mg/kg q12h, reassessed at 48h

*[[Septic arthritis]] and [[osteomyelitis]] *[[Streptococcal toxic shock syndrome]]

*Used for [[Enterococcus]] IE, [[meningitis]], [[septic shock]], [[ascites]], [[AKI]]/[[CKD]], [[pregnancy]], surgical prophylaxis, [[Bur

*** Risk factors include septic shock, female, prior upper GI surgery, and recent antimicrobials

**[[Shock]] at time of presentation |}*† Critical illness dosing should be used for patients with septic shock, admitted to ICU, with endocarditis, or with CNS infection (excluding spina

...medications (and specifically [[tigecycline]] and [[TMP-SMX]]), and septic shock<ref>Taotao Wang, Liyan Miao, Hua Shao, Xiaohua Wei, Miao Yan, Xiaocong Zuo,

*Can range from acute heart failure and cardiogenic shock to more subacute heart failure and dilatation *Caused by both the toxin itself and the septic shock

**Can have heart block and shock *Rare cause of [[osteomyelitis]] and [[septic arthritis]]

* Group A streptococcal toxic shock syndrome should be treated with clindamycin and penicillin * Septic