Oral bioavailability of antimicrobials
From IDWiki
| Antimicrobial | Bioavailability |
|---|---|
| Ciprofloxacin | 70% |
| Levofloxacin | 99% |
| Trimethoprim-sulfamethoxazole | 100% |
| Amoxicillin | 70-80% |
| Amoxicillin-clavulanic acid | 70-80% |
| Cephalexin | 95% |
| Cefadroxil | 90% |
| Cefpodoxime | 46% |
| Cefdinir | 25% |
| Cefixime | 40-50% |
- Note that oral dosing for many medications (e.g. β-lactams) is much lower for oral than for IV formulations, so even a high bioavailability may not guarantee that target levels in serum are reached
Excellent Bioavailability (>90%)
- Ciprofloxacin
- Doxycycline
- Fluconazole
- Levofloxacin
- Linezolid
- Metronidazole
- Minocycline
- Moxifloxacin
- Rifampin
- Trimethoprim-sulfamethoxazole
- Voriconazole
