Grover disease

From IDWiki

Background

Clinical Manifestations

  • Self-limited, papulovesicular rash, most common in older white men
  • Lesions are usually pruritis
  • Can form crusts and keratotic erosions
  • Affects trunk (including back) almost universally, but can also involve proximal and lower extremities, and, occasionally, neck and face
  • Self-resolves over weeks to months, but occasionally can have a chronic fluctuating course lasting years
    • Can recur seasonally in winter and summer

Differential Diagnosis

Management

  • Can include emollients (for dry skin), topical corticosteroids (for pruritus and inflammation), topical vitamin D analogues (if refractory to topical steroids), and oral antihistamines (for pruritus)
  • Second-line options include oral retinoids, systemic corticosteroids, and phototherapy

Further Reading

  • Aldana PC, Khachemoune A. Grover disease: review of subtypes with a focus on management options. Int J Dermatol. 2020 May;59(5):543-550. doi: 10.1111/ijd.14700. PMID: 31724740.