Aspergillus udagawae
From IDWiki
Aspergillus udagawae
Background
- Species of mold within the genus Aspergillus
Clinical Manifestations
- Rare cases of infection in humans
- Cases that I could find in Pubmed in October 2024:
- Fungal canaliculitis in an immunocompetent patient, managed with drainage alone1
- Fungal endocarditis in a patient with ALL that was fatal despite voriconazole2
- Disseminated disease in a patient on chemotherapy for MDS3
- 4 cases of invasive fungal pulmonary infection in 3 patients with CGD and 1 with MDS4
- All patients required long courses with more treatment failures than comparable patients with Aspergillus fumigatus
- 2 patients died
- 2 cases of pulmonary infections in patients with malignancies5
- Bronchial infection in a patient with diabetes mellitus that was successfully treated with voriconazole6
- Fungal keratitis in a healthy patient with clinical failure on itraconazole7
Management
- Increased MICs compared to Aspergillus fumigatus and frequent clinical failures of antifungals
- No clinical breakpoints are available given the rarity of the species
References
- ^ Yuji Nishihara, Takahito Nakamura, Yuki Sakai, Yumiko Ban, Masato Tashiro, Koichi Izumikawa, Kei Kasahara. Isolation of Aspergillus udagawae in Canaliculitis: A Case Report. Medical Mycology Journal. 2023;64(4):99-102. doi:10.3314/mmj.23-00004.
- ^ Atsuko Seki, Atsushi Yoshida, Yoko Matsuda, Mitsuhiro Kawata, Takashi Nishimura, Jun Tanaka, Yoshiki Misawa, Yuta Nakano, Ryoko Asami, Koji Chida, Ken Kikuchi, Tomio Arai. Fatal fungal endocarditis by Aspergillus udagawae : an emerging cause of invasive aspergillosis. Cardiovascular Pathology. 2017;28:14-17. doi:10.1016/j.carpath.2017.02.002.
- ^ 目2021骨髄
- ^ Donald C. Vinh, Yvonne R. Shea, Janyce A. Sugui, Edgardo R. Parrilla‐Castellar, Alexandra F. Freeman, J. William Campbell, Stefania Pittaluga, Pamela A. Jones, Adrian Zelazny, David Kleiner, Kyung J. Kwon‐Chung, Steven M. Holland. Invasive Aspergillosis Due toNeosartorya udagawae. Clinical Infectious Diseases. 2009;49(1):102-111. doi:10.1086/599345.
- ^ Pilar Escribano, Teresa Peláez, Patricia Muñoz, Emilio Bouza, Jesús Guinea. Is Azole Resistance in Aspergillus fumigatus a Problem in Spain?. Antimicrobial Agents and Chemotherapy. 2013;57(6):2815-2820. doi:10.1128/aac.02487-12.
- ^ Hiroshi Gyotoku, Koichi Izumikawa, Hideki Ikeda, Takahiro Takazono, Yoshitomo Morinaga, Shigeki Nakamura, Yoshifumi Imamura, Tomoya Nishino, Taiga Miyazaki, Hiroshi Kakeya, Yoshihiro Yamamoto, Katsunori Yanagihara, Akira Yasuoka, Takashi Yaguchi, Hideaki Ohno, Yoshitsugu Miyzaki, Katsuhiko Kamei, Tetsuro Kanda, Shigeru Kohno. A case of bronchial aspergillosis caused byAspergillus udagawaeand its mycological features. Medical Mycology. 2012;50(6):631-636. doi:10.3109/13693786.2011.639036.
- ^ Brunella Posteraro, Romano Mattei, Fausto Trivella, Andrea Maffei, Antonio Torre, Elena De Carolis, Patrizia Posteraro, Giovanni Fadda, Maurizio Sanguinetti. Uncommon Neosartorya udagawae Fungus as a Causative Agent of Severe Corneal Infection. Journal of Clinical Microbiology. 2011;49(6):2357-2360. doi:10.1128/jcm.00134-11.
