| Virus | Type | Transmission | Chronic liver disease |
|---|---|---|---|
| HAV | ssRNA | fecal-oral | - |
| HBV | DNA | sexual, parenteral, and perinatal | 10% |
| HCV | ssRNA | parenteral | 80% |
| HDV | ssRNA | sexual, parenteral, and perinatal | 5% (coinfection) to 70% (superinfection) |
| HEV | ssRNA | fecal-oral | - |
Differential Diagnosis
- Other causes of hepatitis
- Infectious causes: CMV, HSV, EBV, coxsackievirus, yellow fever virus, Ebola virus, Marburg virus, toxoplasmosis
- Drugs: isoniazid, phenytoin, many others
- Toxins: alcoholic hepatitis
- Others: gallstone, malignancy, genetic disorders
