Urinary tract infection: Difference between revisions

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= Definition =
= Urinary tract infection (UTI, Urosepsis) =
 
 
== Definition ==
 
   
 
* Bacterial infection of the urinary tract, either lower (cystitis) or upper (pyelonephritis)
 
* Bacterial infection of the urinary tract, either lower (cystitis) or upper (pyelonephritis)
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*** Pyuria (>10 WBCs/HPF)
 
*** Pyuria (>10 WBCs/HPF)
   
== Etiology ==
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= Etiology =
   
 
* Typical organisms include:
 
* Typical organisms include:
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** S. saprophicitus
 
** S. saprophicitus
   
== Investigations ==
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= Investigations =
   
 
* Labs
 
* Labs
 
** Urinalysis has high NPV (~100%) if negative for leukocyst esterase and nitrites is negative
 
** Urinalysis has high NPV (~100%) if negative for leukocyst esterase and nitrites is negative
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[[Category:Genitourinary infections]]

Revision as of 21:19, 14 August 2019

Definition

  • Bacterial infection of the urinary tract, either lower (cystitis) or upper (pyelonephritis)
  • When UTI causes sepsis syndrome, often referred to as urosepsis
  • Diagnostic criteria include clinical and laboratory symptoms:
    • Two or more clinical symptoms:
      • Fever > 38ºC
      • Urinary urgency or frequency
      • Acute dysuria
      • Hypogastric pain
      • Costovertebral angle tenderness
    • One or more laboratory finding:
      • Bacteriuria (> 100,000 CFUs/mL)
      • Pyuria (>10 WBCs/HPF)

Etiology

  • Typical organisms include:
    • E. coli
    • S. saprophicitus

Investigations

  • Labs
    • Urinalysis has high NPV (~100%) if negative for leukocyst esterase and nitrites is negative

References

  1. ^  Dimitri M. Drekonja, Barbara Trautner, Carla Amundson, Michael Kuskowski, James R. Johnson. Effect of 7 vs 14 Days of Antibiotic Therapy on Resolution of Symptoms Among Afebrile Men With Urinary Tract Infection. JAMA. 2021;326(4):324. doi:10.1001/jama.2021.9899.