Urinary tract infection: Difference between revisions

Revision as of 11:28, 24 August 2020

Background

Bacterial infection of the urinary tract, either lower (cystitis) or upper (pyelonephritis)
When UTI causes sepsis syndrome, often referred to as urosepsis

Microbiology

Ascending genitourinary infection
Bacteremia
- Staphylococcus aureus
- Candida species

Clinical Manifestations

Diagnostic criteria include clinical and laboratory symptoms:
- Two or more clinical symptoms:
  - Fever > 38ºC
  - Urinary urgency or frequency
  - Acute dysuria
  - Hypogastric pain
  - Costovertebral angle tenderness
- One or more laboratory finding:
  - Bacteriuria (> 100,000 CFUs/mL)
  - Pyuria (>10 WBCs/HPF)

Investigations

Urinalysis has high NPV (~100%) if negative for leukocyst esterase and nitrites

References

^ Dimitri M. Drekonja, Barbara Trautner, Carla Amundson, Michael Kuskowski, James R. Johnson. Effect of 7 vs 14 Days of Antibiotic Therapy on Resolution of Symptoms Among Afebrile Men With Urinary Tract Infection. JAMA. 2021;326(4):324. doi:10.1001/jama.2021.9899.

@@ Line 1: / Line 1: @@
+== Background ==
-* Bacterial infection of the urinary tract, either lower (cystitis) or upper (pyelonephritis)
-* When UTI causes sepsis syndrome, often referred to as urosepsis
+*Bacterial infection of the urinary tract, either lower (cystitis) or upper (pyelonephritis)
-== Criteria ==
+*When UTI causes sepsis syndrome, often referred to as urosepsis
+=== Microbiology ===
-* Diagnostic criteria include clinical and laboratory symptoms:
-** Two or more clinical symptoms:
-*** Fever &gt; 38ºC
-*** Urinary urgency or frequency
-*** Acute dysuria
-*** Hypogastric pain
-*** Costovertebral angle tenderness
-** One or more laboratory finding:
-*** Bacteriuria (&gt; 100,000 CFUs/mL)
-*** Pyuria (&gt;10 WBCs/HPF)
+*Ascending genitourinary infection
-== Etiology ==
+**''[[E. coli]]''
+**''[[S. saprophicitus]]''
+**[[Enterococcus faecalis]]
+*Bacteremia
+**[[Staphylococcus aureus]]
+**[[Candida species]]
+==Clinical Manifestations==
-* Typical organisms include:
-** ''[[E. coli]]''
-** ''[[S. saprophicitus]]''
+*Diagnostic criteria include clinical and laboratory symptoms:
-== Investigations ==
+**Two or more clinical symptoms:
+***Fever &gt; 38ºC
+***Urinary urgency or frequency
+***Acute dysuria
+***Hypogastric pain
+***Costovertebral angle tenderness
+**One or more laboratory finding:
+***Bacteriuria (&gt; 100,000 CFUs/mL)
+***Pyuria (&gt;10 WBCs/HPF)
+==Investigations==
-* Labs
-** Urinalysis has high NPV (~100%) if negative for leukocyst esterase and nitrites is negative
+*Urinalysis has high NPV (~100%) if negative for leukocyst esterase and nitrites
 [[Category:Genitourinary infections]]