Tuberculous adenitis: Difference between revisions

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== Clinical Manifestations ==
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==Clinical Manifestations==
   
=== Paradoxical Reactions ===
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===Paradoxical Reactions===
   
* Paradoxial reaction including paradoxical upgrading reaction
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*Paradoxial reaction including paradoxical upgrading reaction
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*Presents with enlarging lymphadenopathy during or sometimes after treatment
* Occurs in 25% of adenitis
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*Occurs in 25% of adenitis
** Usually during treatment but can occur after treatment
 
* Likely reaction to antigenic stimulus in poorly-cleared disease
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*Likely represents a reaction to an antigenic stimulus in poorly-cleared disease
* In post-treatment paradoxical reactions, need to differentiate from relapse
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*In post-treatment paradoxical reactions, need to differentiate from relapse
* About half will be PCR positive, 20% will be AFB positive, but none are culture positive
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*About half will be PCR positive, 20% will be AFB positive, but none are culture positive
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*90% resolve spontaneously
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*Steroids used commonly
   
 
[[Category:Tuberculosis]]
 
[[Category:Tuberculosis]]

Latest revision as of 09:44, 25 November 2020

Clinical Manifestations

Paradoxical Reactions

  • Paradoxial reaction including paradoxical upgrading reaction
  • Presents with enlarging lymphadenopathy during or sometimes after treatment
  • Occurs in 25% of adenitis
  • Likely represents a reaction to an antigenic stimulus in poorly-cleared disease
  • In post-treatment paradoxical reactions, need to differentiate from relapse
  • About half will be PCR positive, 20% will be AFB positive, but none are culture positive
  • 90% resolve spontaneously
  • Steroids used commonly