Tuberculous adenitis: Difference between revisions
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+ | ==Clinical Manifestations== |
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+ | ===Paradoxical Reactions=== |
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+ | *Paradoxial reaction including paradoxical upgrading reaction |
+ | *Presents with enlarging lymphadenopathy during or sometimes after treatment |
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+ | *Occurs in 25% of adenitis |
− | ** Usually during treatment but can occur after treatment |
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+ | *Likely represents a reaction to an antigenic stimulus in poorly-cleared disease |
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+ | *In post-treatment paradoxical reactions, need to differentiate from relapse |
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+ | *About half will be PCR positive, 20% will be AFB positive, but none are culture positive |
+ | *90% resolve spontaneously |
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+ | *Steroids used commonly |
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[[Category:Tuberculosis]] |
[[Category:Tuberculosis]] |
Latest revision as of 09:44, 25 November 2020
Clinical Manifestations
Paradoxical Reactions
- Paradoxial reaction including paradoxical upgrading reaction
- Presents with enlarging lymphadenopathy during or sometimes after treatment
- Occurs in 25% of adenitis
- Likely represents a reaction to an antigenic stimulus in poorly-cleared disease
- In post-treatment paradoxical reactions, need to differentiate from relapse
- About half will be PCR positive, 20% will be AFB positive, but none are culture positive
- 90% resolve spontaneously
- Steroids used commonly