Syphilis in pregnancy: Difference between revisions

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== Background ==
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* Risk of transmission to fetus
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** Primary and secondary syphilis: 70 to 100%
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** Early latent syphilis: 40%
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** Late latent syphilis: 10%
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==Management==
 
==Management==
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* For primary, secondary, or early latent syphilis: [[Is treated by::benzathine penicillin G]] 2.4 million units IM weekly for 1-2 doses
 
* For late latent, latent syphilis with unknown duration, or tertiary syphilis not involving the CNS: [[Is treated by::benzathine penicillin G]] 2.4 million units IM weekly for 3 doses
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*For primary, secondary, or early latent syphilis: [[Is treated by::benzathine penicillin G]] 2.4 million units IM weekly for 1-2 doses
 
*For late latent, latent syphilis with unknown duration, or tertiary syphilis not involving the CNS: [[Is treated by::benzathine penicillin G]] 2.4 million units IM weekly for 3 doses
* For tertiary neurosyphilis, treat as usual
+
*For tertiary neurosyphilis, treat as usual
* Postpartum, follow guidelines for [[congenital syphilis]] to decide whether and how to treat the neonate
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*Postpartum, follow guidelines for [[congenital syphilis]] to decide whether and how to treat the neonate
   
 
[[Category:Infectious diseases]]
 
[[Category:Infectious diseases]]

Revision as of 14:31, 15 August 2020

Background

  • Risk of transmission to fetus
    • Primary and secondary syphilis: 70 to 100%
    • Early latent syphilis: 40%
    • Late latent syphilis: 10%

Management

  • For primary, secondary, or early latent syphilis: benzathine penicillin G 2.4 million units IM weekly for 1-2 doses
  • For late latent, latent syphilis with unknown duration, or tertiary syphilis not involving the CNS: benzathine penicillin G 2.4 million units IM weekly for 3 doses
  • For tertiary neurosyphilis, treat as usual
  • Postpartum, follow guidelines for congenital syphilis to decide whether and how to treat the neonate