Streptococcus agalactiae: Difference between revisions
From IDWiki
Streptococcus agalactiae
m (→) |
m (→) |
||
| Line 19: | Line 19: | ||
===Older Children and Adults=== |
===Older Children and Adults=== |
||
| − | *Similar spectrum of illness to [[Streptococcus pyogenes]] |
+ | *Similar spectrum of illness to [[Streptococcus pyogenes]], including [[Streptococcal bacteremia|bacteremia]] |
*Rare cause of community-acquired [[Bacterial meningitis|meningitis]] in adults, with high mortality[[CiteRef::van kassel2020co]] |
*Rare cause of community-acquired [[Bacterial meningitis|meningitis]] in adults, with high mortality[[CiteRef::van kassel2020co]] |
||
**Risk factors include immunocompromised state, [[Cerebrospinal fluid leak|CSF leak]], and [[Infective endocarditis|endocarditis]] |
**Risk factors include immunocompromised state, [[Cerebrospinal fluid leak|CSF leak]], and [[Infective endocarditis|endocarditis]] |
||
Latest revision as of 10:34, 12 September 2023
Background
Microbiology
- Gram-positive coccus in chains
- The most common group B Streptococcus of clinical concern
- Identified with the help of a CAMP test, where β-hemolysis is induced by the presence of Staphylococcus aureus
Epidemiology
- Previously the most common cause of neonatal sepsis, until screening and prophylaxis during pregnancy and deliverybecame routine
Clinical Manifestations
Neonatal
- May be either early-onset (< 7 days old) or late-onset (7 to 90 days old)
- Presents with bacteremia, sepsis, pneumonia, and meningitis
Older Children and Adults
- Similar spectrum of illness to Streptococcus pyogenes, including bacteremia
- Rare cause of community-acquired meningitis in adults, with high mortality1
- Risk factors include immunocompromised state, CSF leak, and endocarditis
Management
- Treated with penicillin, amoxicillin, or a first-generation cephalosporin
References
- ^ Merel N. van Kassel, Koen J. van Haeringen, Matthijs C. Brouwer, Merijn W. Bijlsma, Diederik van de Beek. Community-acquired group B streptococcal meningitis in adults. Journal of Infection. 2020;80(3):255-260. doi:10.1016/j.jinf.2019.12.002.
