Spinal hardware infection: Difference between revisions
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+ | == Background == |
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+ | * Also known as postoperative spinal implant infection |
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+ | == Classification == |
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+ | {| class="wikitable" |
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+ | !Classification |
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+ | !Acute Infection |
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+ | !Chronic Infection |
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+ | |- |
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+ | |Pathogenesis: post-interventional |
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+ | |<6 weeks post-interventionally (early onset) |
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+ | |≥6 weeks post-interventionally (late onset) |
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+ | |- |
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+ | |Pathogenesis: hematogenous or per continuitatem |
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+ | |<6 weeks of symptoms |
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+ | |≥6 weeks of symptoms |
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+ | |- |
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+ | |Clinical presentation |
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+ | |acute pain, fever, prolonged wound secretion (>7-10 days), acute neurological deficits |
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+ | |chronic pain, implant migration or loosening, fistula, neurological deficits |
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+ | |- |
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+ | |Typical pathogens |
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+ | |[[Staphylococcus aureus]], [[Streptococcus|Streptococcus species]], [[Gram-negative bacteria]] |
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+ | |[[coagulase-negative staphylococci]], [[Cutibacterium acnes]] |
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+ | |} |
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+ | == Management == |
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+ | * For removal of all hardware, treat with 6 weeks total (at least 2 weeks IV) |
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+ | * For retainment with plan for eradication, treat with 12 weeks total (at least 2 weeks IV) |
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+ | * For single-stage replacement, treat with 12 weeks total (at least 2 weeks IV) |
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+ | * For retainment with plan for eventual removal, treat with at least 2 weeks IV followed by oral suppression until hardware removal |
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+ | * Chronic suppressive antibiotics should be considered with difficult-to-treat organisms |
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+ | |||
== Further Reading == |
== Further Reading == |
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* [https://dx.doi.org/10.4103%2F2152-7806.120783 Infection with spinal instrumentation: Review of pathogenesis, diagnosis, prevention, and management]. ''Surg Neurol Int''. 2013;4(Suppl 5):S392-403. |
* [https://dx.doi.org/10.4103%2F2152-7806.120783 Infection with spinal instrumentation: Review of pathogenesis, diagnosis, prevention, and management]. ''Surg Neurol Int''. 2013;4(Suppl 5):S392-403. |
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+ | *Antibiotic treatment of postoperative spinal implant infections. ''J Spine Surg''. 2020;6(4):785–792. doi: [https://doi.org/10.21037/jss-20-456 10.21037/jss-20-456] |
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[[Category:Trauma and surgical patients]] |
[[Category:Trauma and surgical patients]] |
Revision as of 11:08, 10 March 2022
Background
- Also known as postoperative spinal implant infection
Classification
Classification | Acute Infection | Chronic Infection |
---|---|---|
Pathogenesis: post-interventional | <6 weeks post-interventionally (early onset) | ≥6 weeks post-interventionally (late onset) |
Pathogenesis: hematogenous or per continuitatem | <6 weeks of symptoms | ≥6 weeks of symptoms |
Clinical presentation | acute pain, fever, prolonged wound secretion (>7-10 days), acute neurological deficits | chronic pain, implant migration or loosening, fistula, neurological deficits |
Typical pathogens | Staphylococcus aureus, Streptococcus species, Gram-negative bacteria | coagulase-negative staphylococci, Cutibacterium acnes |
Management
- For removal of all hardware, treat with 6 weeks total (at least 2 weeks IV)
- For retainment with plan for eradication, treat with 12 weeks total (at least 2 weeks IV)
- For single-stage replacement, treat with 12 weeks total (at least 2 weeks IV)
- For retainment with plan for eventual removal, treat with at least 2 weeks IV followed by oral suppression until hardware removal
- Chronic suppressive antibiotics should be considered with difficult-to-treat organisms
Further Reading
- Infection with spinal instrumentation: Review of pathogenesis, diagnosis, prevention, and management. Surg Neurol Int. 2013;4(Suppl 5):S392-403.
- Antibiotic treatment of postoperative spinal implant infections. J Spine Surg. 2020;6(4):785–792. doi: 10.21037/jss-20-456