Small cell lung cancer: Difference between revisions
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| + | == Background == |
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| + | * A form of lung cancer that is almost exclusively in smokers, particularly in heavy smokers |
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| + | === Risk Factors === |
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| + | * '''Tobacco smoking''' |
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| + | * Second-hand smoke |
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| + | * Asbestos exposure |
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| + | * Radon exposure |
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==Staging== |
==Staging== |
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===TMN=== |
===TMN=== |
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Revision as of 12:03, 21 September 2023
Background
- A form of lung cancer that is almost exclusively in smokers, particularly in heavy smokers
Risk Factors
- Tobacco smoking
- Second-hand smoke
- Asbestos exposure
- Radon exposure
Staging
TMN
- Stage 1: a single lesion ≤3 cm with no lymphadenopathy
- Stage 2: ipsilateral lymph nodes and mediastinum
- Stage 3: contralateral lymph nodes and metastases
- Stage 4: distant metastases
VALSG
- Limited stage: disease confined to ipsilateral lung, lymph nodes, and mediastinum, which can be contained within one radiotherapy window
- Extensive stage: metastasis to contralateral lung, contralateral lymph nodes, or distant sites
Management
Stage 1
- Potentially curative
- Surgical resection
- If lymph nodes negative, adjuvant chemotherapy
- If lymph nodes positive, adjuvant chemoradiotherapy
- The adjuvant chemotherapy is platinum-based
Stage 2/Limited Stage
- Not curative
- Early chemoradiotherapy
Stage 3 or 4/Extensive Stage
- Not curative
- Chemotherapy extends median survival from 3 months to 8 to 13 months
- Prophylactic cranial irradiation
