Slow-release oral morphine
From IDWiki
Dosing
BC OUD Guidelines
- Increase doses q48h
- When transitioning from methadone, the eventual dose will usually be 6- to 8-times higher, but generally should start with a 4-times higher dose to be safe
- For other opioids, start with dose of 30 to 60 mg
- Average stable doses are 60 to 1200 mg daily
Missed doses
| Number missed | Action |
|---|---|
| 1 | no change |
| 2 | 40% reduction |
| 3 | 60% reduction |
| 4 | 40 mg or starting dose |
| 5 | re-initiate |
St. Michael's Protocol
| Day | Slow-release morphine | Instant-release morphine |
|---|---|---|
| 1 | 200-300 mg | 30-50 mg po q2h while awake + 30-50 mg po q3h prn |
| 2 | SR dose from Day 1 + 50% of IR dose from Day 3 | 30-50 mg po q2h while awake + 30-50 mg po q3h prn |
| 3 | SR dose from Day 2 | 30-50 mg po q3h prn |
| 4 | SR dose from Day 3 + 50% of IR dose from Day 3 | 30-50 mg po q3h prn |
| 5 | SR dose from Day 4 | 30-50 mg po q3h prn |
| 6 | SR dose from Day 5 + 50% of IR dose from Day 5 | 30-50 mg po q3h prn |
