Sexually-transmitted infection: Difference between revisions
From IDWiki
No edit summary |
No edit summary |
||
(5 intermediate revisions by the same user not shown) | |||
Line 1: | Line 1: | ||
+ | == Background == |
||
+ | |||
+ | * Most common reportable infectious diseases |
||
+ | * Typically treated syndromically |
||
+ | * Often have sequelae such as infertility, cancer, chronic pain, and psychiatric illness |
||
+ | |||
+ | == Microbiology == |
||
+ | |||
+ | ===Bacteria=== |
||
{| class="wikitable" |
{| class="wikitable" |
||
⚫ | |||
!Organism |
!Organism |
||
⚫ | |||
!First-line treatment |
!First-line treatment |
||
!Treatment if allergic |
!Treatment if allergic |
||
!Treatment if pregnant |
!Treatment if pregnant |
||
|- |
|- |
||
⚫ | |||
⚫ | |||
+ | |chlamydia |
||
⚫ | |||
⚫ | |||
⚫ | |||
⚫ | |||
|[[Chlamydia trachomatis]] serovars L1, L2, L3 |
|[[Chlamydia trachomatis]] serovars L1, L2, L3 |
||
⚫ | |||
|[[doxycycline]] 100 mg PO for 3 weeks |
|[[doxycycline]] 100 mg PO for 3 weeks |
||
| |
| |
||
|[[erythromycin]] 500 mg PO qid for 3 weeks |
|[[erythromycin]] 500 mg PO qid for 3 weeks |
||
|- |
|- |
||
− | |Chancroid |
||
|[[Haemophilus ducreyi]] |
|[[Haemophilus ducreyi]] |
||
+ | |chancroid |
||
|[[azithromycin]] 1 g po once |
|[[azithromycin]] 1 g po once |
||
⚫ | |||
|[[ceftriaxone]] 250 mg IM once |
|[[ceftriaxone]] 250 mg IM once |
||
+ | |usual treatment |
||
|- |
|- |
||
− | |Chlamydia |
||
⚫ | |||
⚫ | |||
⚫ | |||
⚫ | |||
⚫ | |||
− | |Donovanosis |
||
|[[Klebsiella granulomatis]] |
|[[Klebsiella granulomatis]] |
||
+ | |granuloma inguinale (donovanosis) |
||
|[[doxycycline]] 100 mg po bid for 3 weeks |
|[[doxycycline]] 100 mg po bid for 3 weeks |
||
| |
| |
||
|[[erythromycin]] |
|[[erythromycin]] |
||
+ | |- |
||
+ | |[[Mycoplasma genitalium]] |
||
+ | |non-gonococcal urethritis/cervicitis |
||
+ | |[[azithromycin]] 500 mg PO on day one, followed by 250 mg PO on days two to five |
||
+ | |[[moxifloxacin]] 400 mg PO daily for 7 days |
||
⚫ | |||
+ | |- |
||
+ | |[[Neisseria gonorrhoeae]] |
||
+ | |gonorrhea |
||
+ | |[[ceftriaxone]] 250 mg IM once + [[azithromycin]] 1 g PO once |
||
+ | |[[gentamicin]] 240 mg IM once + [[azithromycin]] 2 g PO once |
||
+ | |usual treatment |
||
+ | |- |
||
+ | | rowspan="3" |[[Treponema pallidum pallidum]] |
||
+ | |primary, secondary, and EL syphilis |
||
+ | |[[penicillin]] 2.4 MU IM once |
||
+ | |[[doxycycline]] 100 mg PO bid for 14 days |
||
+ | |usual treatment |
||
+ | |- |
||
+ | |LL and tertiary syphilis |
||
+ | |[[penicillin]] 2.4 MU IM weekly for 3 weeks |
||
+ | |desensitization or [[doxycycline]] 100 mg PO bid for 28 days |
||
+ | |usual treatment |
||
+ | |- |
||
+ | |neurosyphilis |
||
+ | |[[penicillin]] 4 MU IV q4h for 10-14 days |
||
+ | |desensitization |
||
+ | |usual treatment |
||
+ | |} |
||
+ | |||
+ | ===Viruses=== |
||
+ | |||
+ | *[[HIV]] |
||
+ | *[[Hepatitis B]] |
||
+ | *[[Hepatitis C]] |
||
+ | *[[Herpes simplex virus]] |
||
+ | *Others: [[molluscum contagiosum]], [[cytomegalovirus]], [[hepatitis A]] |
||
+ | |||
+ | ===Protozoa=== |
||
+ | {| class="wikitable" |
||
+ | !Organism |
||
+ | !Disease |
||
+ | !First-line treatment |
||
+ | !Treatment if allergic |
||
+ | !Treatment if pregnant |
||
+ | |- |
||
+ | |[[Trichomonas vaginalis]] |
||
+ | |trichomoniasis |
||
+ | |[[metronidazole]] 2 g PO once |
||
+ | | |
||
+ | |usual treatment |
||
|} |
|} |
||
+ | |||
+ | ===Ectoparasites=== |
||
+ | |||
+ | *[[Scabies]] |
||
+ | *[[Public lice]] |
||
+ | |||
[[Category:Infectious diseases]] |
[[Category:Infectious diseases]] |
||
[[Category:Sexually-transmitted infections]] |
[[Category:Sexually-transmitted infections]] |
Latest revision as of 11:37, 3 December 2020
Background
- Most common reportable infectious diseases
- Typically treated syndromically
- Often have sequelae such as infertility, cancer, chronic pain, and psychiatric illness
Microbiology
Bacteria
Organism | Disease | First-line treatment | Treatment if allergic | Treatment if pregnant |
---|---|---|---|---|
Chlamydia trachomatis | chlamydia | azithromycin 1 g po once | azithromycin 1 g po once, or amoxicillin 500 mg po tid for 7 days | |
Chlamydia trachomatis serovars L1, L2, L3 | lymphogranuloma venereum | doxycycline 100 mg PO for 3 weeks | erythromycin 500 mg PO qid for 3 weeks | |
Haemophilus ducreyi | chancroid | azithromycin 1 g po once | ceftriaxone 250 mg IM once | usual treatment |
Klebsiella granulomatis | granuloma inguinale (donovanosis) | doxycycline 100 mg po bid for 3 weeks | erythromycin | |
Mycoplasma genitalium | non-gonococcal urethritis/cervicitis | azithromycin 500 mg PO on day one, followed by 250 mg PO on days two to five | moxifloxacin 400 mg PO daily for 7 days | |
Neisseria gonorrhoeae | gonorrhea | ceftriaxone 250 mg IM once + azithromycin 1 g PO once | gentamicin 240 mg IM once + azithromycin 2 g PO once | usual treatment |
Treponema pallidum pallidum | primary, secondary, and EL syphilis | penicillin 2.4 MU IM once | doxycycline 100 mg PO bid for 14 days | usual treatment |
LL and tertiary syphilis | penicillin 2.4 MU IM weekly for 3 weeks | desensitization or doxycycline 100 mg PO bid for 28 days | usual treatment | |
neurosyphilis | penicillin 4 MU IV q4h for 10-14 days | desensitization | usual treatment |
Viruses
- HIV
- Hepatitis B
- Hepatitis C
- Herpes simplex virus
- Others: molluscum contagiosum, cytomegalovirus, hepatitis A
Protozoa
Organism | Disease | First-line treatment | Treatment if allergic | Treatment if pregnant |
---|---|---|---|---|
Trichomonas vaginalis | trichomoniasis | metronidazole 2 g PO once | usual treatment |