View source for Sexually-transmitted infection

== Background ==

* Most common reportable infectious diseases
* Typically treated syndromically
* Often have sequelae such as infertility, cancer, chronic pain, and psychiatric illness

== Microbiology ==

===Bacteria===
{| class="wikitable"
!Organism
!Disease
!First-line treatment
!Treatment if allergic
!Treatment if pregnant
|-
|[[Chlamydia trachomatis]]
|chlamydia
|[[azithromycin]] 1 g po once
|
|[[azithromycin]] 1 g po once, or [[amoxicillin]] 500 mg po tid for 7 days
|-
|[[Chlamydia trachomatis]] serovars L1, L2, L3
|[[lymphogranuloma venereum]]
|[[doxycycline]] 100 mg PO for 3 weeks
|
|[[erythromycin]] 500 mg PO qid for 3 weeks
|-
|[[Haemophilus ducreyi]]
|chancroid
|[[azithromycin]] 1 g po once
|[[ceftriaxone]] 250 mg IM once
|usual treatment
|-
|[[Klebsiella granulomatis]]
|granuloma inguinale (donovanosis)
|[[doxycycline]] 100 mg po bid for 3 weeks
|
|[[erythromycin]]
|-
|[[Mycoplasma genitalium]]
|non-gonococcal urethritis/cervicitis
|[[azithromycin]] 500 mg PO on day one, followed by 250 mg PO on days two to five
|[[moxifloxacin]] 400 mg PO daily for 7 days
|
|-
|[[Neisseria gonorrhoeae]]
|gonorrhea
|[[ceftriaxone]] 250 mg IM once + [[azithromycin]] 1 g PO once
|[[gentamicin]] 240 mg IM once + [[azithromycin]] 2 g PO once
|usual treatment
|-
| rowspan="3" |[[Treponema pallidum pallidum]]
|primary, secondary, and EL syphilis
|[[penicillin]] 2.4 MU IM once
|[[doxycycline]] 100 mg PO bid for 14 days
|usual treatment
|-
|LL and tertiary syphilis
|[[penicillin]] 2.4 MU IM weekly for 3 weeks
|desensitization or [[doxycycline]] 100 mg PO bid for 28 days
|usual treatment
|-
|neurosyphilis
|[[penicillin]] 4 MU IV q4h  for 10-14 days
|desensitization
|usual treatment
|}

===Viruses===

*[[HIV]]
*[[Hepatitis B]]
*[[Hepatitis C]]
*[[Herpes simplex virus]]
*Others: [[molluscum contagiosum]], [[cytomegalovirus]], [[hepatitis A]]

===Protozoa===
{| class="wikitable"
!Organism
!Disease
!First-line treatment
!Treatment if allergic
!Treatment if pregnant
|-
|[[Trichomonas vaginalis]]
|trichomoniasis
|[[metronidazole]] 2 g PO once
|
|usual treatment
|}

===Ectoparasites===

*[[Scabies]]
*[[Public lice]]

[[Category:Infectious diseases]]
[[Category:Sexually-transmitted infections]]