Screening before prolonged immunosuppressive therapy: Difference between revisions

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* Tuberculosis
+
* [[Tuberculosis]]
** Screen if pred 15mg daily for 1+ month
+
** Screen if planning [[prednisone]] ≥15mg daily for 1+ month
** TB skin test (false positive if BCG and needs a 48h repeat)
+
** [[Tuberculin skin test|TB skin test]] (false positive if [[BCG]] and needs a 48h repeat)
*** Still useful to test up after up to two weeks of ≤20mg daily prednisone
+
*** Still useful to test up after up to two weeks of ≤20mg daily [[prednisone]]
** IGRA (expensive)
+
** [[Interferon-gamma release assay|IGRA]] (expensive)
* Hepatitis B
+
* [[Hepatitis B]]
** Screen if >7.5mg prednisone daily
+
** Screen if planning [[prednisone]] >7.5mg daily
 
** Treat if HbSag positive or if HbCAb and HBV-DNA positive
 
** Treat if HbSag positive or if HbCAb and HBV-DNA positive
** Prophylaxis with lemivudine for 6 months after the immune suppression is done
+
** Prophylaxis with [[lamivudine]] for 6 months after the immune suppression is done
* Strongyloides
+
* [[Strongyloides]]
 
** Screen with serology if has ever travelled to an endemic country
 
** Screen with serology if has ever travelled to an endemic country
   

Latest revision as of 11:08, 12 December 2023

  • Tuberculosis
    • Screen if planning prednisone ≥15mg daily for 1+ month
    • TB skin test (false positive if BCG and needs a 48h repeat)
      • Still useful to test up after up to two weeks of ≤20mg daily prednisone
    • IGRA (expensive)
  • Hepatitis B
    • Screen if planning prednisone >7.5mg daily
    • Treat if HbSag positive or if HbCAb and HBV-DNA positive
    • Prophylaxis with lamivudine for 6 months after the immune suppression is done
  • Strongyloides
    • Screen with serology if has ever travelled to an endemic country