Schistosoma: Difference between revisions
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Schistosoma
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Revision as of 07:28, 16 August 2019
Schistosoma spp. (schistosomiasis)
Definition
- Infection with a species of the genus Schistosoma
Species
- S. mansoni: liver and gut
- S. haematobium: GU/pelvis
- S. japonicum: liver and gut
- S. mekongi: Mekong basin
Risk Factors
- Fresh water exposure in endemic countries
Clinical Presentation
Investigations
- Labs
- CBC, showing eosinophilia
- Schisto serology (only positive 6 weeks after infection)
- Egg detection in stool, urine, semen, or tissue biopsy
- Imaging
- Eggs can cause granulomatous disease in various organs
- Bladder polyps and obstruction may be seen on ultrasound
Management
- Acute
- Praziquantel 40mg/kg/d
- Can cause nausea, dizziness, and fever
- Praziquantel 40mg/kg/d
- Chronic
- Prevention
Prognosis
- Increased risk of squamous cell carcinoma, which increase with young age at infection, duration of infection, high burden of infection, and bladder wall fibrosis
