SPRINT Frailty Index

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Item Source Item Response (points) Notes
1 AAH Self-rated general health Excellent (0)
Very Good (0.25)
Good (0.5)
Fair (0.75)
Poor (1)
2 AAH Does your health limit you now inactivities,moderate activities, such as moving a table, pushing a vacuum cleaner, bowling, or playing gold? No, not limited at all (0)
Yes, limited a little (0.5)
Yes, limited a lot (1)
3 AAH Does your health limit you now in climbing several flights of stairs? No, not limited at all (0)
Yes, limited a little (0.5)
Yes, limited a lot (1)
4 AAH During the past 4 weeks, have you accomplished less than you would like as a result of your physical health? No, none of the time (0)
Yes, a little of the time (0.25)
Yes, some of the time (0.5)
Yes, most of the time (0.75)
Yes, all of the time (1)
5 AAH During the past 4 weeks, did you not do work or other activities as carefully as usual due to emotional problems? No, none of the time (0)
Yes, a little bit of the time (0.25)
Yes, some of the time (0.5)
Yes, most of the time (0.75)
Yes, all of the time (1)
6 HYVET During the past 4 weeks, how much did pain interfere with your normal work? Not at all (0)
A little bit (0.25)
Moderately (0.5)
Quite a bit (0.75)
Extremely (1)
7 AAH How much of the time during the past 4 weeks did you have a lot of energy? All of the time (0)
Most of the time (0.2)
A good bit of the time (0.4)
Some of the time (0.6)
A little of the time (0.8)
None of the time (1)
8 AAH How much of the time during the past 4 weeks have you felt downhearted and blue? None of the time (0)
A little of the time (0.2)
Some of the time (0.4)
A good bit of the time (0.6)
Most of the time (0.8)
All of the time (1)
9 HYVET During the past 4 weeks, how much of the time has your physical health or emotional problems interfered with your social activities? None of the time (0)
A little of the time (0.25)
Some of the time (0.5)
A good bit of the time (0.75)
All of the time (1)
10 HYVET Self-care I have no problems with self-care (0)
I have some problems washing or dressing myself (0.5)
I am unable to wash or dress myself (1)
11 AAH Over the last two weeks, have you had trouble falling or staying asleep, or sleeping too much? Not at all (0)
Several day (0.33)
More than half the days (0.67)
Nearly every day (1)
12 HYVET Smoking status Never smoker (0)
Former smoker (0.5)
Current smoker (1)
13 AAH Self-reported history of stroke No (0)
Yes (1)
14 AAH Self-reported history of diabetes No (0)
Yes (1)
15 AAH Self-reported history of heart attack No (0)
Yes (1)
16 AAH Self-reported history of cancer No (0)
Yes (1)
17 AAH Self-reported history of heart failure No (0)
Yes (1)
18 AAH Self-reported history of angina No (0)
Yes (1)
19 HYVET Self-reported history of atrial fibrillation or atrial fibrillation detected on ECG reading No (0)
Yes (1)
20 AAH Chronic kidney disease (CKD) eGFR <60 (1) CKD-EPI equation
21 SPRINT Albuminuria ≥30 and <300 mg/g Cr (0.5)
≥300 mg/g Cr (1)
22 HYVET HDL <0.4 or >1.5 mmol/l (1)
23 HYVET Total Cholesterol <3.5 or >7 mmol/l (1)
24 HYVET Potassium <3.5 or >6 mmol/l (1)
25 HYVET Sodium <135 or >150 mmol/l (1)
26 HYVET Glucose <2.8 or >11 mmol/l (1)
27 HYVET Blood Urea <3 or >7.5 mmol/l (1)
28 HYVET Overweight/Obese BMI ≥25 and <30 (0.5)
BMI ≥30 (1)
29 HYVET Underweight BMI <18.5 (1)
30 HYVET Systolic BP ≥180 mmHg (1)
31 HYVET Diastolic BP ≥90 mmHg (1)
32 HYVET Orthostatic hypotension Difference in seated-to-standing SBP ≥20 or DBP ≥10 (1)
33 AAHS Global Cognitive Status (MoCA) < age- and education-specific 25th percentile (1)
34 HYVET MoCA Orientation Score ≤4 out of 6 (1)
35 SPRINT Logical Memory Delayed Recall 1.5 SD or more below normative mean for age (!) a
36 SPRINT Digit Symbol Copy 1.5 SD or more below normative mean for age (1) b
37 SPRINT Gait Speed ≥1 m/s (0)
≥0.8 to <1 ms/s (0.33)
≥0.6 to <0.8 m/s (0.67)
<0.6 m/s (1)
  • (AAH) Items included based on FI from the African-American Health Study
  • (HYVET) Items included based on FI from the Hypertension in the Very
  • Elderly Trial (SPRINT) Items unique to SPRINT not included in AAH or HYVET FIs
  • a WAIS III Manual Table A.1
  • b WMS-IV Manual Table 2.19