Rothia: Difference between revisions
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Rothia
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* Rare causes of bacteremia and line infection, most in immunocompromised patients |
* Rare causes of bacteremia and line infection, most in immunocompromised patients |
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| + | ** Almost always caused by [[Rothia mucilaginosa]]<ref>Ramanan P, Barreto JN, Osmon DR, Tosh PK. Rothia bacteremia: a 10-year experience at Mayo Clinic, Rochester, Minnesota. J Clin Microbiol. 2014 Sep;52(9):3184-9. doi: [https://doi.org/10.1128/JCM.01270-14 10.1128/JCM.01270-14]. Epub 2014 Jun 20. PMID: 24951810; PMCID: PMC4313135.</ref> |
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| − | ** Almost always caused by [[Rothia mucilaginosa]] |
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* Case reports of endocarditis, meningitis, peritonitis, bone and joint infections, pneumonia, skin and soft tissue infection, endophthalmitis, and prosthetic joint infection |
* Case reports of endocarditis, meningitis, peritonitis, bone and joint infections, pneumonia, skin and soft tissue infection, endophthalmitis, and prosthetic joint infection |
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Latest revision as of 14:44, 6 September 2022
Background
- Genus of Gram-positive coccobacilli that can form filamentous branches
- Normal oral flora in humans
- Associated with dental caries and periodontal disease
- Species of importance include:
- Rothia mucilaginosa (most common cause of disease in humans)
- Rothia dentocariosa
- Rothia aeria
- Rothia nasimurium
- Rothia amarae
- Risk factors for infection include immunocompromise, particularly hematologic malignancy and severe neutropenia
- Other risk factors include diabetes mellitus, alcohol use disorder, chronic liver disease, and HIV infection
Clinical Manfestations
- Rare causes of bacteremia and line infection, most in immunocompromised patients
- Almost always caused by Rothia mucilaginosa[1]
- Case reports of endocarditis, meningitis, peritonitis, bone and joint infections, pneumonia, skin and soft tissue infection, endophthalmitis, and prosthetic joint infection
- ↑ Ramanan P, Barreto JN, Osmon DR, Tosh PK. Rothia bacteremia: a 10-year experience at Mayo Clinic, Rochester, Minnesota. J Clin Microbiol. 2014 Sep;52(9):3184-9. doi: 10.1128/JCM.01270-14. Epub 2014 Jun 20. PMID: 24951810; PMCID: PMC4313135.
