Rickettsia akari: Difference between revisions
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Rickettsia akari
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| + | ==Background== |
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| + | |||
* Causes '''rickettsialpox''' |
* Causes '''rickettsialpox''' |
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| − | = |
+ | ===Microbiology=== |
| − | * |
+ | *Disease caused by ''Rickettsia akari'', an intracellular Gram-negative bacterium |
| − | * |
+ | *Unlike most rickettsiae, it has a plasmid |
| − | = |
+ | ===Epidemiology=== |
| − | * |
+ | *Transmitted by the house mouse mite (''Liponyssoides sanguineus'') |
| − | ** |
+ | **Rodents are the reservoir |
| − | * |
+ | *Most cases are in New York, but it is found worldwide |
| − | * |
+ | *Most likely rickettsiosis to be found in Ontario |
| − | * |
+ | *Homelessness and IV drug use are risk factors |
| − | = |
+ | ==Clinical Manifestations== |
| − | * |
+ | *Incubation period of [[Usual incubation period::7 to 14 days]] |
| − | * |
+ | *Present with [[Causes::fever]], [[Causes::vesicular rash]], and [[Causes::eschar]] |
| − | ** |
+ | **Headache also common |
| − | * |
+ | *The [[Causes::eschar]] is painless, and appears as a papule about a week after innoculation, followed by vesicle that dries and leaves a brown or black eschar |
| − | * |
+ | *The rash is vesicular, but may be papulovesicular or any other type of rash |
| − | ** |
+ | **Lesions leaves black crust and heal without scarring |
| − | ** |
+ | **Spares palms and soles |
| − | ** |
+ | **Resolves in two to three weeks |
| − | * |
+ | *May find leukocytosis |
| − | = |
+ | ==Diagnosis== |
| − | * |
+ | *Detection of a four-fold rise in convalescent titres by complement fixation or indirect fluorescent antibodies |
| − | = |
+ | ==Management== |
| − | * |
+ | *Usually self-limited, resolving in 7 to 10 days, though antibiotics help |
| − | * Doxycycline 100 mg po bid for 2 to 5 days and 48 h after fever resolves |
+ | *[[Is treated by::Doxycycline]] 100 mg po bid for 2 to 5 days and 48 h after fever resolves |
{{DISPLAYTITLE:''Rickettsia akari''}} |
{{DISPLAYTITLE:''Rickettsia akari''}} |
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Latest revision as of 10:08, 15 October 2020
Background
- Causes rickettsialpox
Microbiology
- Disease caused by Rickettsia akari, an intracellular Gram-negative bacterium
- Unlike most rickettsiae, it has a plasmid
Epidemiology
- Transmitted by the house mouse mite (Liponyssoides sanguineus)
- Rodents are the reservoir
- Most cases are in New York, but it is found worldwide
- Most likely rickettsiosis to be found in Ontario
- Homelessness and IV drug use are risk factors
Clinical Manifestations
- Incubation period of 7 to 14 days
- Present with fever, vesicular rash, and eschar
- Headache also common
- The eschar is painless, and appears as a papule about a week after innoculation, followed by vesicle that dries and leaves a brown or black eschar
- The rash is vesicular, but may be papulovesicular or any other type of rash
- Lesions leaves black crust and heal without scarring
- Spares palms and soles
- Resolves in two to three weeks
- May find leukocytosis
Diagnosis
- Detection of a four-fold rise in convalescent titres by complement fixation or indirect fluorescent antibodies
Management
- Usually self-limited, resolving in 7 to 10 days, though antibiotics help
- Doxycycline 100 mg po bid for 2 to 5 days and 48 h after fever resolves
