Rheumatoid arthritis: Difference between revisions
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| − | == |
+ | == Background == |
* Seropositive inflammatory arthritis |
* Seropositive inflammatory arthritis |
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=== Initial === |
=== Initial === |
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| − | * Methotrexate |
+ | * [[Methotrexate]] |
* Biologics |
* Biologics |
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| − | ** Anti-TNF: adalimumab |
+ | ** [[Tumour necrosis factor-α inhibitors|Anti-TNF]]: [[adalimumab]] |
| − | ** T-cell costimulatory inhibitor: abatacept |
+ | ** T-cell costimulatory inhibitor: [[abatacept]] |
| − | ** IL-6 antagonist: tocilizumab |
+ | ** IL-6 antagonist: [[tocilizumab]] |
| − | ** IL-1 antagonist: anakinra |
+ | ** IL-1 antagonist: [[anakinra]] |
| − | ** B-cell depleting agents: rituximab |
+ | ** B-cell depleting agents: [[rituximab]] |
| − | ** JAK1/2/3 inhibitor: tofacitinib |
+ | ** JAK1/2/3 inhibitor: [[tofacitinib]] |
=== Chronic === |
=== Chronic === |
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* Vaccination |
* Vaccination |
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| − | ** Can give dead vaccines: |
+ | ** Can give dead vaccines: influenza, pneumococcus, HBV |
| − | ** Can give live zoster vaccine with methotrexate but not biologics |
+ | ** Can give live zoster vaccine with [[methotrexate]] but not biologics |
| − | ** Avoid other live vaccines in both methotrexate and biologicals |
+ | ** Avoid other live vaccines in both [[methotrexate]] and biologicals |
[[Category:Rheumatology]] |
[[Category:Rheumatology]] |
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Latest revision as of 20:56, 16 March 2022
Background
- Seropositive inflammatory arthritis
Management
Initial
- Methotrexate
- Biologics
- Anti-TNF: adalimumab
- T-cell costimulatory inhibitor: abatacept
- IL-6 antagonist: tocilizumab
- IL-1 antagonist: anakinra
- B-cell depleting agents: rituximab
- JAK1/2/3 inhibitor: tofacitinib
Chronic
- Vaccination
- Can give dead vaccines: influenza, pneumococcus, HBV
- Can give live zoster vaccine with methotrexate but not biologics
- Avoid other live vaccines in both methotrexate and biologicals
