Pyomyositis

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Revision as of 17:31, 13 July 2022 by Aidan (talk | contribs) (Created page with "=== Background === * Pus within an individual muscle group, often associated with tropical climates * Risk factors include tropical climates, HIV, diabetes mellitus * May have a firm woody feel * CK often normal ==== Microbiology ==== * Staphylococcus aureus in 90% * Group A Streptococcus and Enterobacterales are also possible === Investigations === * MRI establishes the diagnosis, though CT and US are useful * Get blood cultures (positive in 5-3...")
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Background

  • Pus within an individual muscle group, often associated with tropical climates
  • Risk factors include tropical climates, HIV, diabetes mellitus
  • May have a firm woody feel
  • CK often normal

Microbiology

Investigations

  • MRI establishes the diagnosis, though CT and US are useful
  • Get blood cultures (positive in 5-30%)
  • Repeat imaging if persistently bacteremic in order to find other infections

Management

  • Needs incision and drainage
  • Vancomycin or cefazolin is appropriate empiric therapy
  • Add Gram-negative coverage if immunocompromised or open trauma
  • Adjust based on microbiology
  • Duration is with IV until better and not bacteremic, then oral to complete 2-3 weeks