Post-transplant acute limbic encephalitis
From IDWiki
- Limbic encephalitis syndrome following hematopoietic stem cell transplantation
Background
- Caused by HHV-6
Clinical Presentation
- Onset 2 weeks to 2 months after transplant
- Presents with confusion, amnesia, hallucinations
- Can cause seizures
- Hyponatremia is common
Management
- Treat seizures with antiepileptic medications
- Treat any possible concomitant risk factors such as hyponytremia
- Antivirals: acyclovir, ganciclovir, or foscarnet for 10 days to 4 weeks
