Platypnea-orthodeoxia

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Definition

  • Orthostatic right-to-left shunt across an ASD or PFO resulting in desaturation and dyspnea on sitting upright

Differential Diagnosis

  • Cardiac
    • ASD
    • PFO
    • Intrapulmonary shunting
    • Pericardial effusion
    • Constrictive pericarditis
  • Pulmonary
    • Emphysema
    • Amiodarone pulmonary toxicity
    • Pneumonectomy
  • Cirrhosis
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