Nocardia: Difference between revisions
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Nocardia
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*Severe: [[Is treated by::TMP-SMX]] plus either [[Is treated by::amikacin]] or [[Is treated by::imipenem]] |
*Severe: [[Is treated by::TMP-SMX]] plus either [[Is treated by::amikacin]] or [[Is treated by::imipenem]] |
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*Other antimicrobials include [[Is treated by::ceftriaxone]], [[Is treated by::minocycline]], and [[Is treated by:: linezolid]] |
*Other antimicrobials include [[Is treated by::ceftriaxone]], [[Is treated by::minocycline]], and [[Is treated by:: linezolid]] |
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| + | === Duration === |
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| + | * Isolated cutaneous infection in immunocompetent host: 3 to 6 months |
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| + | * Isolated cutaneous infection in immunocompromised host: 6 to 12 months |
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| + | * Serious pulmonary infection: 6 to 12 months or longer |
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| + | * Any non-cutaneous disease in immunocompromised host: at least 12 months, and possibly lifelong suppression |
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Revision as of 13:55, 9 September 2021
Background
Microbiology
- Beaded Gram-positive partially acid-fast bacillus
Management
- Mild to moderate: TMP-SMX
- Immunocompetent: 5-10 mg/kg split tid to qid
- Immunocompromised: 15 mg/kg split tid to qid
- Severe: TMP-SMX plus either amikacin or imipenem
- Other antimicrobials include ceftriaxone, minocycline, and linezolid
Duration
- Isolated cutaneous infection in immunocompetent host: 3 to 6 months
- Isolated cutaneous infection in immunocompromised host: 6 to 12 months
- Serious pulmonary infection: 6 to 12 months or longer
- Any non-cutaneous disease in immunocompromised host: at least 12 months, and possibly lifelong suppression
