Nevirapine: Difference between revisions

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(Created page with " == Pediatric Dosing == === Neonatal HIV prophylaxis === * Dosed by body surface area * ≥34 weeks gestation at birth: 150 mg/m<sup>2</sup> PO once daily for 2 weeks, then q1...")
 
(→â€: added three-dose regimen)
 
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* <34 weeks: 10 mg/m<sup>2</sup> PO once daily for 2 weeks, then q12h for 2 weeks
 
* <34 weeks: 10 mg/m<sup>2</sup> PO once daily for 2 weeks, then q12h for 2 weeks
 
* Need to monitor serum trough levels at 7 and 14 days
 
* Need to monitor serum trough levels at 7 and 14 days
  +
* For alternative three-dose regimen:
  +
** 8 mg/dose (1.5-2 kg) or 12 mg (>2 kg) within 48 hours of birth, repeated 48 hours after first dose and 96 hours after second dose
   
 
[[Category:HIV]]
 
[[Category:HIV]]

Latest revision as of 23:30, 15 November 2019

Pediatric Dosing

Neonatal HIV prophylaxis

  • Dosed by body surface area
  • ≥34 weeks gestation at birth: 150 mg/m2 PO once daily for 2 weeks, then q12h for 2 weeks
  • <34 weeks: 10 mg/m2 PO once daily for 2 weeks, then q12h for 2 weeks
  • Need to monitor serum trough levels at 7 and 14 days
  • For alternative three-dose regimen:
    • 8 mg/dose (1.5-2 kg) or 12 mg (>2 kg) within 48 hours of birth, repeated 48 hours after first dose and 96 hours after second dose