Monoclonal gammopathy of unknown significance

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Also see [[|Multiple myeloma]]

Definition

  • Proliferation of a single gamma globulin

Differential Diagnosis

  • Neoplasm
    • Lymphoma
      • Lymphoplasmacytic lymphoma (Waldenstrom's macroglobulinemia)
      • Chronic lymphocytic leukemia
      • Follicular lymphoma
      • Diffuse large B-cell lymphoma
    • Multiple myeloma
  • Infection
    • Hepatitis C
    • HIV
  • Connective tissue diseases
    • Rheumatoid arthritis (RA)
    • Systemic lupus erythematosus (SLE)

Management

  • Depends on underlying health
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