Macacine alphaherpesvirus 1

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Revision as of 08:13, 15 October 2019 by Aidan (talk | contribs) (Aidan moved page Herpes B virus to Macacine alphaherpesvirus 1)

Background

  • Also known as macacine herpesvirus 1, macacine alphaherpesvirus 1, cercopithecine herpesvirus 1, CHV-1), herpes B virus, monkey B virus, herpesvirus simiae and herpesvirus B

History

  • First diagnosed in a researcher in 1933

Microbiology

  • Double-stranded DNA virus
  • Alphaherpesvirus, in the same family as HSV

Clinical Presentation

  • Typically via bite or scratch of macaque monkey
    • Asymptomatic or similar presentation to HSV in the monkey
    • Seroprevalence reaches 100% in some populations of macaques
  • Three clinical forms:
    • Flu-like illness followed by CNS symptoms
    • Local symptoms (itching, tingling, numbness, or pain) at the inoculation site, with or without vesicular rash and regional lymphadenopathy
    • Peripheral or central nervous system symptoms, with meningismus, vomiting, confusion, cranial nerve palsies

Diagnosis

Management

References

  1. ^  F. P. Gay, M. Holden. Isolation of a Herpes Virus from Several Cases of Epidemic Encephalitis.. Experimental Biology and Medicine. 1933;30(8):1051-1053. doi:10.3181/00379727-30-6788.
  2. ^  Joshua Fierer. Herpes B Virus Encephalomyelitis Presenting as Ophthalmic Zoster. Annals of Internal Medicine. 1973;79(2):225. doi:10.7326/0003-4819-79-2-225.