Etiologies
- Osteomyelitis, including syphilitic osteomyelitis
- Fibrous dysplasia
- Eosinophilic granuloma, a form of Langerhans cell histiocytosis
- Enchondroma
- Giant cell tumour
- Non-ossifying fibroma
- Osteoblastoma
- Aneurysmal bone cyst
- Solitary bone cyst, typically well-defined and central, typically in proximal humerus and femur, and in patients less than 30 years
- Hyperparathyroidism (Brown tumour)
- Chondroblastoma or chondromyxoid fibroma, cartilagenous tumours of the epiphysis
- Metastasis
- Myeloma
- Pseudocyst/normal variant, particularly in the greater tuberosity of the humerus, the calcaneus, and the radial tuberosity
Further Reading
- Subramanian S, Viswanathan VK. Lytic Bone Lesions. [Updated 2022 Oct 22]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK539837/
