Kaposi sarcoma-associated herpesvirus: Difference between revisions

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(Created page with "== Background == * Seroprevalence variés by geography and group ** US general population 1-5% ** US men who have sex with men 15-20% ** US MSM with HIV 30-35% ** Some Mediterranean countries 10-20% ** Sub-Saharan African countries 30-80% == Clinical Manifestations == * Mostly asymptomatic * Kaposi sarcoma == Management == * See Kaposi sarcoma Category:Human herpesviruses")
 
(added a few other clinical manifestations)
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* Mostly asymptomatic
 
* Mostly asymptomatic
 
* [[Kaposi sarcoma]]
 
* [[Kaposi sarcoma]]
  +
* Primary effusion lymphoma (PEL)
  +
** Causes effusions isolated within the pleural, pericardial, or abdominal cavities
  +
** Occasionally causes mass lesions and extracavitary disease within skin, hematopoietic organs, and the GI
  +
* Multicentric Castleman disease (MCD)
  +
** Causes systemic symptoms including fever and night sweats, generalized adenopathy, fever, and hepatosplenomegaly
   
 
== Management ==
 
== Management ==

Revision as of 14:14, 1 October 2022

Background

  • Seroprevalence variés by geography and group
    • US general population 1-5%
    • US men who have sex with men 15-20%
    • US MSM with HIV 30-35%
    • Some Mediterranean countries 10-20%
    • Sub-Saharan African countries 30-80%

Clinical Manifestations

  • Mostly asymptomatic
  • Kaposi sarcoma
  • Primary effusion lymphoma (PEL)
    • Causes effusions isolated within the pleural, pericardial, or abdominal cavities
    • Occasionally causes mass lesions and extracavitary disease within skin, hematopoietic organs, and the GI
  • Multicentric Castleman disease (MCD)
    • Causes systemic symptoms including fever and night sweats, generalized adenopathy, fever, and hepatosplenomegaly

Management