Kaposi sarcoma

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Revision as of 13:25, 1 October 2022 by Aidan (talk | contribs) (Created page with "==Background== * A tumour associated with HHV-8 * Closely associated with advanced HIV ===ACTG Staging=== * Based on extent of tumour (T), immune status (I), and severity of systemic illness (S) {| !Criterion !Lower Risk (0) !Higher risk (1) |- |Tumour (T) |Confined to skin and/or lymph nodes and/or minimal oral disease (non-nodular KS confined to palate) |Tumor-associated edema or ulceration; extensive oral KS; gastrointestinal KS; or KS in other non-nodal vis...")
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Background

  • A tumour associated with HHV-8
  • Closely associated with advanced HIV

ACTG Staging

  • Based on extent of tumour (T), immune status (I), and severity of systemic illness (S)
Criterion Lower Risk (0) Higher risk (1)
Tumour (T) Confined to skin and/or lymph nodes and/or minimal oral disease (non-nodular KS confined to palate) Tumor-associated edema or ulceration; extensive oral KS; gastrointestinal KS; or KS in other non-nodal viscera
Immune status (I) CD4 cell count >200/µL CD4 cell count <200/µL
Systemic illness (S) No history of OI or thrush; no "B" symptoms; and Karnofsky performance status >70 History of OI or thrush; "B" symptoms present; Karnofsky performance status <70; or other HIV-related illness (eg, neurologic disease, lymphoma)