Ivermectin: Difference between revisions
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+ | ==Background== |
===Indications=== |
===Indications=== |
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*Crusted [[scabies]] |
*Crusted [[scabies]] |
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+ | ===Pharmacokinetics and Pharmacodynamics=== |
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+ | *Does not cross blood-brain barrier |
==Dosing== |
==Dosing== |
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*Usual dose is 150-200 mcg/kg PO or SC once |
*Usual dose is 150-200 mcg/kg PO or SC once |
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+ | ==Safety== |
===Adverse Effects=== |
===Adverse Effects=== |
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| + | *Most common side effects are mild, including pruritus (25.3%), headache (13.9%), and dizziness (7.5%) |
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*Occasionally causes Mazzotti-type reaction in [[onchocerciasis]], characterized by fever, pruritus, tender lymphadenopathy, arthralgias and myalgias |
*Occasionally causes Mazzotti-type reaction in [[onchocerciasis]], characterized by fever, pruritus, tender lymphadenopathy, arthralgias and myalgias |
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*Rarely causes hypotension |
*Rarely causes hypotension |
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Latest revision as of 14:23, 11 April 2021
Background
Indications
Pharmacokinetics and Pharmacodynamics
- Does not cross blood-brain barrier
Dosing
- Usual dose is 150-200 mcg/kg PO or SC once
Safety
Adverse Effects
- Most common side effects are mild, including pruritus (25.3%), headache (13.9%), and dizziness (7.5%)
- Occasionally causes Mazzotti-type reaction in onchocerciasis, characterized by fever, pruritus, tender lymphadenopathy, arthralgias and myalgias
- Rarely causes hypotension
