Ivermectin: Difference between revisions

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== Indications ==
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==Background==
   
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===Indications===
* [[Strongyloides]]
 
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* [[Onchocerciasis]]
 
 
*[[Strongyloides]]
* [[Cutaneous larva migrans]]
 
 
*[[Onchocerciasis]]
* Crusted [[scabies]]
 
 
*[[Cutaneous larva migrans]]
 
*Crusted [[scabies]]
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  +
===Pharmacokinetics and Pharmacodynamics===
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*Does not cross blood-brain barrier
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==Dosing==
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*Usual dose is 150-200 mcg/kg PO or SC once
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  +
==Safety==
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===Adverse Effects===
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*Most common side effects are mild, including pruritus (25.3%), headache (13.9%), and dizziness (7.5%)
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*Occasionally causes Mazzotti-type reaction in [[onchocerciasis]], characterized by fever, pruritus, tender lymphadenopathy, arthralgias and myalgias
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*Rarely causes hypotension
   
 
[[Category:Antihelminthics]]
 
[[Category:Antihelminthics]]

Latest revision as of 14:23, 11 April 2021

Background

Indications

Pharmacokinetics and Pharmacodynamics

  • Does not cross blood-brain barrier

Dosing

  • Usual dose is 150-200 mcg/kg PO or SC once

Safety

Adverse Effects

  • Most common side effects are mild, including pruritus (25.3%), headache (13.9%), and dizziness (7.5%)
  • Occasionally causes Mazzotti-type reaction in onchocerciasis, characterized by fever, pruritus, tender lymphadenopathy, arthralgias and myalgias
  • Rarely causes hypotension