Infective endocarditis

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Infective endocarditis (IE)

See also [IDSA: IE Management 2015](/Infectious Diseases/IDSA Guidelines/IE Management 2015/IE Management 2015.md)

Diagnosis

  • Infection of heart valves

Organisms

  • Staphylococcus aureus
  • Viridans group streptococci
  • Coagulase-negative staphylococci
  • Other streptococci
  • Enterococci
  • HACEK group
  • Fungi

Presentation

  • [Modified Duke criteria](Modified Duke criteria.md)
  • IVDU: Viridans group streptococci and Pseudomonas aeroginosa
  • Colon cancer: Streptococcus bovis and Clostridium septicum

Treatment

  • MSSA native valve endocarditis
    • Cloxacillin or cefazolin
    • OR vanco/dapto
  • MSSA prosthetic valve endocarditis
    • Clox PLUS rifampin PLUS 2 weeks of gentamicin
    • OR vanco/dapto, other things
    • 6 weeks