Infections after hematopoietic stem cell transplantation
From IDWiki
Timeline of infections
| Time | Risk factors | Bacteria | Viruses | Fungi | Parasites |
|---|---|---|---|---|---|
| Pre-engraftment day 0 to 30 |
Neutropenia, mucositis, and central lines | GPCs and GNBs | BK virus, HSV, and resp/enteric viruses | Candida and Aspergillus | Strongyloides |
| Early post-engraftment to day 100 |
Immunosuppresing meds, acute GVHD, central lines | GPCs, encapsulated bacteria, Listeria, Salmonella, Nocardia | HSV, CMV, HHV-6, adenovirus, resp/enteric viruses | Aspergillus, other molds, PJP | Stronyloides, Toxoplasma |
| Mid post-engraftment to 1 year |
Immunosuppressing meds, chronic GVHD | Encapsulated bacteria, Listeria, Salmonella, Nocardia | VZV, EBV (and PTLD), CMV, resp/enteric viruses | Aspergillus, other molds, PJP | |
| Late post-engraftment after 1 year |
Immuneosuppresing meds, chronic GVHD | Encapsulated bacteria, Listeria, Salmonella, Nocardia | VZV, CMV, resp/enteric viruses |
Further Reading
- Life-threatening Infection in Transplant Recipients. Crit Care Clin. 2013 Oct;29(4):953-73. doi: [heept://doi.org/10.1016/j.ccc.2013.06.012 10.1016/j.ccc.2013.06.012]
