Inadvertent breast milk exposure: Difference between revisions

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* Women often pump breast milk for neonates in hospital, and mix-ups occasionally happen
 
* Women often pump breast milk for neonates in hospital, and mix-ups occasionally happen
 
* Risk of infection is low, but includes [[Hepatitis B virus|hepatitis B]], [[Human immunodeficiency virus|HIV]], and [[Human T-lymphotropic virus|HTLV]]
 
* Risk of infection is low, but includes [[Hepatitis B virus|hepatitis B]], [[Human immunodeficiency virus|HIV]], and [[Human T-lymphotropic virus|HTLV]]
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== Investigations ==
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* From donor mother, send the following:
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** HBsAg and HIV serology, STAT
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** HCV and HTLV serology
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** CMV serology (if the recipient baby is less than 32 weeks old)
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* If the donor mother is positive for any of the above, also test the recipient's mother
   
 
== Management ==
 
== Management ==
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* Inform infection control, nurse manager, etc.
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* Investigations as above, and management as below
 
{| class="wikitable"
 
{| class="wikitable"
 
! Donor mother !! Recipient mother !! Suggested management
 
! Donor mother !! Recipient mother !! Suggested management
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| HIV positive || Continue standard prophylactic therapy
 
| HIV positive || Continue standard prophylactic therapy
 
|}
 
|}
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* If given, HBIG should be given within 24 hours and vaccine within 7 days
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* If given, HIV prophylaxis should be started within 1 to 2 hours of exposure, but can be started up to 48 hours later
   
 
[[Category:Infection_prevention_and_control]]
 
[[Category:Infection_prevention_and_control]]

Latest revision as of 23:02, 12 November 2019

  • Women often pump breast milk for neonates in hospital, and mix-ups occasionally happen
  • Risk of infection is low, but includes hepatitis B, HIV, and HTLV

Investigations

  • From donor mother, send the following:
    • HBsAg and HIV serology, STAT
    • HCV and HTLV serology
    • CMV serology (if the recipient baby is less than 32 weeks old)
  • If the donor mother is positive for any of the above, also test the recipient's mother

Management

  • Inform infection control, nurse manager, etc.
  • Investigations as above, and management as below
Donor mother Recipient mother Suggested management
Hepatitis B
HBsAg negative HBsAg negative Routine immunization for hepatitis B
HBsAg positive Administer hepatitis B vaccine and immune globulin (HBIG), if not yet given
HBsAg positive HBsAg negative Administer hepatitis B vaccine, if not yet given, and HBIG
HBsAg positive Administer hepatitis B vaccine and HBIG, if not yet given
HIV
HIV negative HIV negative Routine care
HIV positive Continue standard prophylactic therapy
HIV positive HIV negative Could consider zidovudine in high-risk situations, though no routine recommendation
HIV positive Continue standard prophylactic therapy
  • If given, HBIG should be given within 24 hours and vaccine within 7 days
  • If given, HIV prophylaxis should be started within 1 to 2 hours of exposure, but can be started up to 48 hours later