Imipenem-relebactam: Difference between revisions
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*Active against Enterobacterales including ESBL, AmpC, and KPC, Bacteroides, MDR Pseudomonas |
*Active against Enterobacterales including ESBL, AmpC, and KPC, Bacteroides, MDR Pseudomonas |
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*No activity against many Gram-positives or afermentative Gram-negatives |
*No activity against many Gram-positives or afermentative Gram-negatives |
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| + | [[Category:Carbapenems]] |
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| + | [[Category:β-lactamase inhibitors]] |
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Latest revision as of 10:02, 26 August 2020
Background
Mechanism of Action
- Relebactam improves activity against beta-lactamases including class A and C
- Also includes cilastatin, as per usual with imipenem
Spectrum of Activity
- Active against Enterobacterales including ESBL, AmpC, and KPC, Bacteroides, MDR Pseudomonas
- No activity against many Gram-positives or afermentative Gram-negatives
