Genital ulcer disease: Difference between revisions

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(Created page with "== Differential Diagnosis == === Sexually-Transmitted Infections === {| class="wikitable" !Organism !Disease !% !Incubation !Treatment |- |Herpes simplex virus | |95% |2-...")
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== Differential Diagnosis ==
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==Differential Diagnosis==
   
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=== Sexually-Transmitted Infections ===
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===Sexually-Transmitted Infections===
 
{| class="wikitable"
  
{| class="wikitable"
 
!Organism
  
!Organism
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|-
  
|-
 
|[[Herpes simplex virus]]
  
|[[Herpes simplex virus]]
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|genital herpes
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|
  
 
|95%
  
|95%
 
|2-7 days (1ΒΊ)
  
|2-7 days (1ΒΊ)
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|<1%
  
|<1%
 
|1-180 days
  
|1-180 days
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|[[azithromycin]] 1 g PO weekly for 21 days (and healed)
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|
  
 
|}
  
|}
   
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=== Other Infectious Causes ===
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===Other Infectious Causes===
   
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* Fungal
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*Fungal
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** [[Candida]]
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**[[Candida]]
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** Deep fungal infection
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**Deep fungal infection
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* Viral
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*Viral
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** [[Cytomegalovirus]]
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**[[Cytomegalovirus]]
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** [[Varicella-zoster virus]]
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**[[Varicella-zoster virus]]
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** [[Epstein-Barr virus]]
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**[[Epstein-Barr virus]]
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* Bacterial
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*Bacterial
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** [[Staphylococcus species]]
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**[[Staphylococcus species]]
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** [[Streptococcus species]]
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**[[Streptococcus species]]
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** [[Salmonella species]]
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**[[Salmonella species]]
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** [[Pseudomonas species]]
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**[[Pseudomonas species]]
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** [[Mycobacterium species]]
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**[[Mycobacterium species]]
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* [[Scabies]]
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*[[Scabies]]
   
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=== Non-Infectious Causes ===
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===Non-Infectious Causes===
   
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* Bullous dermatoses
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*Bullous dermatoses
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** Non-autoimmune
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**Non-autoimmune
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*** [[Contact dermatitis]]
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***[[Contact dermatitis]]
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*** [[Erythema multiforme]] (usually secondary to [[HSV]])
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***[[Erythema multiforme]] (usually secondary to [[HSV]])
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*** [[Toxic epidermolysis]]
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***[[Toxic epidermolysis]]
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** Autoimmune
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**Autoimmune
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*** [[Pemphigus]]
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***[[Pemphigus]]
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*** [[Cicatricial pemphigoid|Pemphigoid]]
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***[[Cicatricial pemphigoid|Pemphigoid]]
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* Non-bullous dermatoses
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*Non-bullous dermatoses
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** Nonspecific [[vulvitis]]/[[balanitis]]
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**Nonspecific [[vulvitis]]/[[balanitis]]
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** [[Aphthous ulcer]]
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**[[Aphthous ulcer]]
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** [[Lichen planus]]
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**[[Lichen planus]]
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** [[Lichen sclerosus]]
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**[[Lichen sclerosus]]
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** [[Behçet disease]]
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**[[Behçet disease]]
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** [[Pyoderma gangrenosum]]
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**[[Pyoderma gangrenosum]]
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** [[Fixed drug eruption]]
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**[[Fixed drug eruption]]
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** [[Systemic lupus erythematosus]]
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**[[Systemic lupus erythematosus]]
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** [[Crohn disease]]
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**[[Crohn disease]]
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** [[Vasculitis]]
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**[[Vasculitis]]
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* Malignancy
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*Malignancy
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** [[Squamous cell carcinoma]]
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**[[Squamous cell carcinoma]]
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** [[Vulvar intraepithelial neoplasia]]
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**[[Vulvar intraepithelial neoplasia]]
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** Extramammary [[Paget disease]]
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**Extramammary [[Paget disease]]
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** [[Basal cell carcinoma]]
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**[[Basal cell carcinoma]]
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** [[Lymphoma]]
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**[[Lymphoma]]
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** [[Leukemia]]
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**[[Leukemia]]
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** [[Langerhans cell histiocytosis]]
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**[[Langerhans cell histiocytosis]]
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* Trauma
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*Trauma
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* Idiopathic (12-51%)
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*Idiopathic (12-51%)
   
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== Further Reading ==
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==Further Reading==
   
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* [https://www.canada.ca/en/public-health/services/infectious-diseases/sexual-health-sexually-transmitted-infections/canadian-guidelines/sexually-transmitted-infections/canadian-guidelines-sexually-transmitted-infections-21.html Management and treatment of specific syndromes – Genital Ulcer Disease (GUD)]. ''Canadian Guidelines on Sexually Transmitted Infections''. 2016.
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*[https://www.canada.ca/en/public-health/services/infectious-diseases/sexual-health-sexually-transmitted-infections/canadian-guidelines/sexually-transmitted-infections/canadian-guidelines-sexually-transmitted-infections-21.html Management and treatment of specific syndromes – Genital Ulcer Disease (GUD)]. ''Canadian Guidelines on Sexually Transmitted Infections''. 2016.
   
 
[[Category:Infectious diseases]]
  
[[Category:Infectious diseases]]

Revision as of 21:59, 7 August 2020

Differential Diagnosis

Sexually-Transmitted Infections

Organism Disease % Incubation Treatment
Herpes simplex virus genital herpes 95% 2-7 days (1ΒΊ)
Treponema pallidum pallidum primary syphilis 1% 3-90 days penicillin 2.4 MU IM once
Haemophilus ducreyi chancroid <1% 5-14 days
Chlamydia trachomatis serovars L1-L3 lymphogranuloma venereum <1% 3-30 days doxycycline 100 mg PO bid for 21 days
Klebsiella granulomatis donovanosis (granuloma inguinale) <1% 1-180 days azithromycin 1 g PO weekly for 21 days (and healed)

Other Infectious Causes

Non-Infectious Causes

Further Reading

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