Galactomannan: Difference between revisions
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+ | *Quantitative analysis of galactomannan levels in either bronchoalveolar lavage or blood that is used to diagnose invasive aspergillosis |
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+ | ==Pathophysiology== |
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+ | *Galactomannan is a component of the cell wall of [[Aspergillus]] that is released when the organism is actively dividing |
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+ | ==Interpretation== |
| + | *Usual cuttoff is 0.5, but the higher it is, the more likely it is to be true positive |
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+ | *Bronchoalveolar lavage more sensitive than serum |
| − | * False-positives in pip/tazo, amox/clav, Penicillium spp., Histoplasma spp. |
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| + | *False-positives in [[piperacillin-tazobactam]], [[amoxicillin-clavulanic acid]], [[Penicillium]] ([[Talaromyces]]), [[Histoplasma]], [[Fusarium]], [[Paecilomyces]], possibly [[Nocardia]] |
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[[Category:Diagnostics]] |
[[Category:Diagnostics]] |
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Latest revision as of 13:22, 10 March 2023
- Quantitative analysis of galactomannan levels in either bronchoalveolar lavage or blood that is used to diagnose invasive aspergillosis
Pathophysiology
- Galactomannan is a component of the cell wall of Aspergillus that is released when the organism is actively dividing
Interpretation
- Usual cuttoff is 0.5, but the higher it is, the more likely it is to be true positive
- Bronchoalveolar lavage more sensitive than serum
- False-positives in piperacillin-tazobactam, amoxicillin-clavulanic acid, Penicillium (Talaromyces), Histoplasma, Fusarium, Paecilomyces, possibly Nocardia
