Galactomannan: Difference between revisions
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+ | *Quantitative analysis of galactomannan levels in either bronchoalveolar lavage or blood that is used to diagnose invasive aspergillosis |
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+ | ==Pathophysiology== |
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+ | *Galactomannan is a component of the cell wall of [[Aspergillus species]] that is released when the organism is actively dividing |
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+ | ==Interpretation== |
| + | *Usual cuttoff is 0.5, but the higher it is, the more likely it is to be true positive |
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| − | * |
+ | *Bronchoalveolar lavage more sensitive than serum |
| − | * False-positives in pip/tazo, amox/clav, Penicillium spp., Histoplasma spp. |
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| + | *False-positives in [[piperacillin-tazobactam]], [[amoxicillin-clavulanic acid]], [[Penicillium species]] ([[Talaromyces species]]), [[Histoplasma species]], [[Fusarium species]], [[Paecilomyces species]] |
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[[Category:Diagnostics]] |
[[Category:Diagnostics]] |
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Revision as of 19:29, 21 September 2020
- Quantitative analysis of galactomannan levels in either bronchoalveolar lavage or blood that is used to diagnose invasive aspergillosis
Pathophysiology
- Galactomannan is a component of the cell wall of Aspergillus species that is released when the organism is actively dividing
Interpretation
- Usual cuttoff is 0.5, but the higher it is, the more likely it is to be true positive
- Bronchoalveolar lavage more sensitive than serum
- False-positives in piperacillin-tazobactam, amoxicillin-clavulanic acid, Penicillium species (Talaromyces species), Histoplasma species, Fusarium species, Paecilomyces species
