Dosing of antimicrobials in obesity: Difference between revisions

Revision as of 11:04, 9 December 2019

Statistic	Equation (Male)	Equation (Female)	Notes
Body mass index (BMI) (kg/m²)	weight, kg / (height, m)²
Body surface area (BSA) (m²)	(height, cm × weight, kg / 3600)^1/2
Ideal body weight (IBW) (kg)	50 + 2.3 × (inches over 5 ft)	45.5 + 2.3 × (inches over 5 ft)
Adjusted body weight (ABW) (kg)	IBW + C × (TBW - IBW)		C = 0.3 to 0.4
Lean body weight (LBW) (kg)	9270 × TBW / 6680 + 216 x BMI	9270 × TBW / 8780 + 244 x BMI
Fat-free weight (FFW) (kg)	0.00139 × (height, cm)² - 0.0801 × R + 0.187 × TBW + 39.83	0.00151 × (height, cm)² - 0.0344 × R + 0.14 × TBW - (0.158 × age) + 20.387	R = resistance

Drug	Usual Dose	Obesity	Max dose
Amoxicillin		1 g PO q8h	No data
Ampicillin		2 g IV q4h

Drug	Usual Dose	Obesity	Max dose
Cefazolin	1-2 g IV q8h	2-3 g IV q6-8h	No data; 12 g daily

@@ Line 29: / Line 29: @@
 | 0.00151 × (height, cm)<sup>2</sup> - 0.0344 × R + 0.14 × TBW - (0.158 × age) + 20.387
 | R = resistance
+|}
+== Antibiotics ==
+=== Penicillins ===
+{| class="wikitable"
+! Drug !! Usual Dose !! Obesity !! Max dose
+|-
+| [[Amoxicillin]]
+|
+| 1 g PO q8h
+| No data
+|-
+| [[Ampicillin]]
+|
+| 2 g IV q4h
+|
+|}
+=== Cephalosporins ===
+{| class="wikitable"
+! Drug !! Usual Dose !! Obesity !! Max dose
+|-
+| [[Cefazolin]]
+| 1-2 g IV q8h
+| 2-3 g IV q6-8h
+| No data; 12 g daily
 |}