Dobutamine: Difference between revisions
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| + | ==Background== |
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| − | == Classification == |
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+ | *Synthetic catecholamine with B1 and B2 agonist activity, causing inotropy and chronotropy and mild vasodilation |
| − | == |
+ | ===Indications=== |
| − | * |
+ | *Systolic heart failure causing cardiogenic shock, especially if bradycardic |
| − | * |
+ | *Also used for cardiac stress testing |
| + | === Pharmacokinetics and Pharmacodynamics === |
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| − | == Starting == |
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+ | ==Dosing== |
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| − | == Half-life == |
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| + | ==Safety== |
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| − | == |
+ | === Adverse Drug Reactions === |
| − | * |
+ | *Tachycardia |
| − | * |
+ | *Hypertension or hypotension |
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+ | *Increased ventricular response in atrial fibrillation |
| − | * |
+ | *Ventricular arrhythmias |
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+ | *Can worsen myocardial ischemia |
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+ | *Eosinophilic myocarditis |
[[Category:Cardiology]] |
[[Category:Cardiology]] |
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+ | [[Category:Medications]] |
Latest revision as of 11:11, 14 April 2021
Background
- Synthetic catecholamine with B1 and B2 agonist activity, causing inotropy and chronotropy and mild vasodilation
Indications
- Systolic heart failure causing cardiogenic shock, especially if bradycardic
- Also used for cardiac stress testing
Pharmacokinetics and Pharmacodynamics
- Half-life is a few minutes
Dosing
- Start at 2 to 20 mcg/kg/min (max 40)
Safety
Adverse Drug Reactions
- Tachycardia
- Hypertension or hypotension
- Increased ventricular response in atrial fibrillation
- Ventricular arrhythmias
- Can worsen myocardial ischemia
- Eosinophilic myocarditis
