Diabetic foot infection: Difference between revisions
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===Microbiology=== |
===Microbiology=== |
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*Anaerobes are more likely to be involved in deeper, more chronic ulcers |
*Anaerobes are more likely to be involved in deeper, more chronic ulcers |
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+ | ==Management== |
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+ | *Osteomyelitis |
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+ | **Traditionally, 6 weeks of parenteral therapy |
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+ | **May be able to shorten to 3 weeks if adequately debrided, based on more recent evidence[[CiteRef::gariani2020th]] |
==Further Reading== |
==Further Reading== |
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Revision as of 15:23, 13 January 2021
Background
Microbiology
- Typically polymicrobial, including:
- Staphylococcus species
- Streptococcus species
- Proteobacteria (Gram-negative bacterial genus that includes enterics)
- Anaerobes
- Anaerobes are more likely to be involved in deeper, more chronic ulcers
Management
- Osteomyelitis
- Traditionally, 6 weeks of parenteral therapy
- May be able to shorten to 3 weeks if adequately debrided, based on more recent evidence1
Further Reading
- The Neuropathic Diabetic Foot Ulcer Microbiome IsAssociated With Clinical Factors. Diabetes. 2013;62:923-930.
References
- ^ Karim Gariani, Truong-Thanh Pham, Benjamin Kressmann, François R Jornayvaz, Giacomo Gastaldi, Dimitrios Stafylakis, Jacques Philippe, Benjamin A Lipsky, İlker Uçkay. Three versus six weeks of antibiotic therapy for diabetic foot osteomyelitis: A prospective, randomized, non-inferiority pilot trial. Clinical Infectious Diseases. 2020. doi:10.1093/cid/ciaa1758.
