Diabetic foot infection: Difference between revisions

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== Microbiology ==
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== Background ==
   
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===Microbiology===
* Typically involve a combination of ''Staphylococci'', ''Streptococci'', Proteobacteria (Gram-negative bacterial genus that includes enterics), and anaerobes
 
* Anaerobes are more likely to be involved in deeper, more chronic ulcers
 
   
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*Typically polymicrobial, including:
== Further Reading ==
 
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**[[Staphylococcus species]]
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**[[Streptococcus species]]
 
**[[Proteobacteria]] (Gram-negative bacterial genus that includes enterics)
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**[[Anaerobes]]
 
*Anaerobes are more likely to be involved in deeper, more chronic ulcers
   
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== Management ==
* [https://doi.org/10.2337/db12-0771 The Neuropathic Diabetic Foot Ulcer Microbiome IsAssociated With Clinical Factors]. ''Diabetes''. 2013;62:923-930.
 
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* Osteomyelitis
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** Traditionally, 6 weeks of parenteral therapy
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** May be able to shorten to 3 weeks based on more recent evidence[[CiteRef::gariani2020th]]
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==Further Reading==
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*[https://doi.org/10.2337/db12-0771 The Neuropathic Diabetic Foot Ulcer Microbiome IsAssociated With Clinical Factors]. ''Diabetes''. 2013;62:923-930.
   
 
[[Category:Skin and soft tissue infections]]
 
[[Category:Skin and soft tissue infections]]

Revision as of 15:22, 13 January 2021

Background

Microbiology

Management

  • Osteomyelitis
    • Traditionally, 6 weeks of parenteral therapy
    • May be able to shorten to 3 weeks based on more recent evidence1

Further Reading

References

  1. ^  Karim Gariani, Truong-Thanh Pham, Benjamin Kressmann, François R Jornayvaz, Giacomo Gastaldi, Dimitrios Stafylakis, Jacques Philippe, Benjamin A Lipsky, İlker Uçkay. Three versus six weeks of antibiotic therapy for diabetic foot osteomyelitis: A prospective, randomized, non-inferiority pilot trial. Clinical Infectious Diseases. 2020. doi:10.1093/cid/ciaa1758.