Diabetes mellitus: Difference between revisions

Revision as of 15:13, 20 August 2020

Definition

Disorder of glucose metabolism resulting in chronically elevated serum glucose levels

Causes and Classification

Type 1: absolute insulin deficiency from beta-islet cell destruction
- Type 1a: autoimmune beta-islet destruction
- Type 1b: beta-islet destruction without known cause
- Latent autoimmune diabetes in adults (LADA): insulin resistance that progresses to autoimmune diabetes and insulin dependency over several years
Type 2: insulin resistance and varying degrees of insulin deficiency
Genetic conditions
- Maturity-onsent diabetes of the young (MODY): autosomal dominant condition that causes type 2 diabetes in those under 25
- Wolfram syndrome: diabetes insipidus, diabetes mellitus, optic atrophy, and deafness (DIDMOAD)
Exocrine pancreas disorders
Drug-induced
- Steroids
- Many others
Stiff-person syndrome
Anti-insulin receptor antibodies

@@ Line 1: / Line 1: @@
-== Definition ==
+==Definition==
-* Disorder of glucose metabolism resulting in chronically elevated serum glucose levels
+*Disorder of glucose metabolism resulting in chronically elevated serum glucose levels
-== Causes and Classification ==
+==Causes and Classification==
-* '''Type 1:''' absolute insulin deficiency from beta-islet cell destruction
+*'''[[Type 1 diabetes mellitus|Type 1]]:''' absolute insulin deficiency from beta-islet cell destruction
-** '''Type 1a:''' autoimmune beta-islet destruction
+**'''Type 1a:''' autoimmune beta-islet destruction
-** '''Type 1b:''' beta-islet destruction without known cause
+**'''Type 1b:''' beta-islet destruction without known cause
-** '''Latent autoimmune diabetes in adults (LADA):''' insulin resistance that progresses to autoimmune diabetes and insulin dependency over several years
+**'''Latent autoimmune diabetes in adults (LADA):''' insulin resistance that progresses to autoimmune diabetes and insulin dependency over several years
-* '''Type 2:''' insulin resistance and varying degrees of insulin deficiency
+*'''[[Type 2 diabetes mellitus|Type 2]]:''' insulin resistance and varying degrees of insulin deficiency
-* Genetic conditions
+*Genetic conditions
-** '''Maturity-onsent diabetes of the young (MODY):''' autosomal dominant condition that causes type 2 diabetes in those under 25
+**'''[[Maturity-onsent diabetes of the young]] (MODY):''' autosomal dominant condition that causes type 2 diabetes in those under 25
-** '''Wolfram syndrome:''' diabetes insipidus, diabetes mellitus, optic atrophy, and deafness (DIDMOAD)
+**'''[[Wolfram syndrome]]:''' [[diabetes insipidus]], [[diabetes mellitus]], [[optic atrophy]], and [[deafness]] (DIDMOAD)
-* Exocrine pancreas disorders
+*Exocrine pancreas disorders
-** Cystic fibrosis
+**[[Cystic fibrosis]]
-** Hereditary hemochronatosis
+**[[Hereditary hemochromatosis]]
-** Chronic pancreatitis
+**[[Chronic pancreatitis]]
-** Fibrocalculous pancreatic diabetes
+**[[Fibrocalculous pancreatic diabetes]]
-* Drug-induced
+*Drug-induced
-** Steroids
+**[[Steroids]]
-** Many others
+**Many others
-* Stiff-person syndrome
+*[[Stiff-person syndrome]]
-* Anti-insulin receptor antibodies
+*Anti-insulin receptor antibodies
 [[Category:Endocrinology]]