Daptomycin: Difference between revisions
From IDWiki
(Created page with "* Cyclic lipopeptide antibiotic that is active against Gram-positive bacteria * Mechanism of action is to depolarize the cell membrane * Bactericidal Category:Cyclic lipope...") |
No edit summary |
||
| Line 1: | Line 1: | ||
| + | == Background == |
||
| ⚫ | |||
| + | |||
| ⚫ | |||
| ⚫ | |||
| ⚫ | |||
| + | |||
| + | === Mechanism of Action === |
||
| + | |||
| ⚫ | |||
| + | |||
| + | == Pharmacokinetics and Pharmacodynamics == |
||
| + | |||
| ⚫ | |||
| + | *Distributes well into soft tissues and musculoskeletal system, as well as urine |
||
| + | **Poor CNS penetration |
||
| + | **Good lung penetration, but is inactivated by lung surfactant and should not be used to treat pneumonia |
||
[[Category:Cyclic lipopeptides]] |
[[Category:Cyclic lipopeptides]] |
||
Revision as of 13:59, 21 September 2020
Background
- Cyclic lipopeptide antibiotic that is active against Gram-positive bacteria
Mechanism of Action
- Mechanism of action is to depolarize the cell membrane
Pharmacokinetics and Pharmacodynamics
- Bactericidal
- Distributes well into soft tissues and musculoskeletal system, as well as urine
- Poor CNS penetration
- Good lung penetration, but is inactivated by lung surfactant and should not be used to treat pneumonia
